Author

P. van Run

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 5

Signature Assays, Organisms & Methods

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Approach:experimental assay· 5 Research Focus:host-pathogen & immune response· 5 Organism:mouse· 3 Organism:non-human primate· 1

Frequent Co-Authors

B. Rockx· 4 shared M. Koopmans· 4 shared M. M. Lamers· 3 shared T. Kuiken· 3 shared B. Haagmans· 2 shared B. L. Haagmans· 2 shared C. GeurtsvanKessel· 2 shared D. de Meulder· 2 shared

Activity by Year

2020-2022 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 42 mutual co-author links

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4 shared papersMicrobiology

B. Rockx

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5 papers

Recent·Most cited

Differences in neuroinflammation in the olfactory bulb between D614G, Delta and Omicron BA.1 SARS-CoV-2 variants in the hamster model

L. Bauer, M. Rissmann, F. Benavides, L. Leijten, L. Begeman, E. Veldhuis Kroeze, P. van Run, M. P. G. Koopmans, B. Rockx, D. van Riel

The paper compares neuroinflammation in the olfactory bulb of hamsters infected with D614G, Delta, and Omicron BA.1 SARS-CoV-2 variants, finding differences in neuroinvasion and neurovirulence.

bioRxiv · Mar 24, 2022 · PreprintMicrobiology

Pulmonary lesions following inoculation with the SARS-CoV-2 Omicron BA.1 (B.1.1.529) variant in Syrian golden hamsters

M. Rissmann, D. Noack, D. van Riel, K. S. Schmitz, R. D. de Vries, P. van Run, M. M. Lamers, C. GeurtsvanKessel, M. Koopmans, R. Fouchier, T. Kuiken, B. Haagmans, B. Rockx

This study inoculates Syrian golden hamsters with SARS-CoV-2 Omicron BA.1 to compare its pathogenicity and viral shedding to Delta, finding reduced clinical signs and viral shedding but still pneumonia, with pre-existing immunity offering protection.

bioRxiv · Mar 15, 2022Microbiology

Susceptibility of rabbits to SARS-CoV-2

A. Z. Mykytyn, M. M. Lamers, N. M. A. Okba, T. I. Breugem, D. Schipper, P. B. van den Doel, P. van Run, G. van Amerongen, L. de Waal, M. Koopmans, K. J. Stittelaar, J. van den Brand, B. L. Haagmans

This study shows rabbits can be infected with SARS-CoV-2 and shed infectious virus from the nose and throat.

bioRxiv · Aug 27, 2020Microbiology

SARS-CoV-2 neutralizing human antibodies protect against lower respiratory tract disease in a hamster model

B. L. Haagmans, D. Noack, N. M. A. Okba, W. LI, C. Wang, T. Bestebroer, R. de Vries, S. Herfst, D. de Meulder, P. van Run, M. M. Lamers, B. Rijnders, C. Rokx, F. J. M. van Kuppeveld, F. Grosveld, , B. Rockx

This study shows that high-dose convalescent plasma or monoclonal antibodies protect hamsters from SARS-CoV-2-induced lower respiratory disease, but lower doses are ineffective.

bioRxiv · Aug 24, 2020Microbiology

Comparative Pathogenesis Of COVID-19, MERS And SARS In A Non-Human Primate Model

B. Rockx, T. Kuiken, S. Herfst, T. Bestebroer, M. Lamers, D. de Meulder, G. van Amerongen, J. van de Brand, N. Okba, D. Schipper, P. van Run, L. Leijten, E. Verschoor, B. Verstrepen, J. Langermans, , B. Haagmans

This study compares the pathogenesis of SARS-CoV-2, MERS-CoV, and SARS-CoV in non-human primates, showing SARS-CoV-2 causes a COVID-19-like disease with prolonged viral excretion without clinical signs.

bioRxiv · Mar 17, 2020Microbiology