Author

C. Kerr

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Pharmacology & Toxicology· 2 Biochemistry· 1 Bioengineering· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Research Focus:drug response / drug discovery· 3 Research Focus:cell type annotation· 2 Research Focus:differential expression· 1 Organism:E. coli· 1 Organism:human· 1 Assay:organoid / primary culture· 1 Assay:proteomics· 1

Frequent Co-Authors

D. A. Fletcher· 2 shared D. W. Gray· 2 shared F. Bellany· 2 shared S. Lang· 2 shared A. Hope· 1 shared A. Plater· 1 shared A.-P. Petit· 1 shared B. Baragana· 1 shared

Activity by Year

2019-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 36 mutual co-author links

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2 shared papersPharmacology & Toxicology

D. A. Fletcher

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Application of an NMR/crystallography fragment screening platform for the assessment and rapid discovery of new HIV-CA binding fragments

S. Lang, D. A. Fletcher, A.-P. Petit, N. Luise, P. K. Fyfe, F. Zuccotto, D. Porter, A. Hope, F. Bellany, C. Kerr, C. J. MacKenzie, P. G. Wyatt, D. W. Gray

The paper uses NMR and crystallography to identify and assess new HIV-CA binding fragments, leading to the discovery of two compounds with improved binding properties.

bioRxiv · Dec 1, 2023Pharmacology & Toxicology

The Quest to Identify USP8 Inhibitors for Parkinsons Disease, a PAINful Experience.

S. Lang, F. Bellany, D. Lin, D. S. Barrett, K. R. Cartmill, D. A. Fletcher, C. Kerr, A. Plater, B. Forte, B. Baragana, P. Dixit, M. M. Littleson, M. C. Wheldon, D. W. Gray, F. Cunningham

The paper identifies PAINS in a USP8 inhibitor screening campaign for Parkinson's disease and discusses interference mechanisms affecting assay reliability.

bioRxiv · Sep 5, 2023 · PreprintPharmacology & Toxicology

Human Cardiac Organoids to Model COVID-19 Cytokine Storm Induced Cardiac Injuries

D. C. Arhontoulis, C. Kerr, D. Richards, K. Tjen, N. Hyams, J. A. Jones, K. Deleon-Pennell, D. R. Menick, D. Lindner, D. Westermann, Y. Mei

This study uses human cardiac organoids to model COVID-19-induced cardiac injuries by simulating cytokine storm effects and evaluates potential therapeutic interventions.

bioRxiv · Jan 31, 2022Bioengineering

Profiling the E. coli Membrane Interactome Captured in Peptidisc Libraries

J. W. Young, G. Stacey, M. Carlson, I. Wason, Z. Zhao, D. G. Rattray, N. Scott, C. Kerr, M. Babu, L. Foster, F. Duong

This paper uses peptidisc libraries and PCP to profile E. coli membrane interactomes, identifying novel interactions not detectable with detergent-based methods.

bioRxiv · Jul 17, 2019Biochemistry