Author

L. Wallace

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 3 Microbiology· 2 Ecology· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 6 Organism:human· 5 Research Focus:cell type annotation· 4 Assay:bulk RNA-seq· 3 Research Focus:differential expression· 3 Assay:proteomics· 3 Approach:deep learning· 2 Organism:bacteria (other)· 1

Frequent Co-Authors

C. G. Hubert· 2 shared H. Keshishian· 2 shared S. A. Carr· 2 shared S. Shakya· 2 shared A. Bain· 1 shared A. D. Nunn· 1 shared A. Gromovsky· 1 shared A. Henders· 1 shared

Activity by Year

2019-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 10 mutual co-author links

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Curved chords = mutual co-authorship

2 shared papersCancer Biology

C. G. Hubert

Mutual co-authors in cluster

Author profile →

7 papers

Recent·Most cited

Cardiovascular symptoms of PASC are associated with trace-level cytokines that affect the function of human pluripotent stem cell derived cardiomyocytes

J. Sinclair, C. Vedelago, F. Ryan, M. Carney, M. Redd, M. Lynn, B. Grubor-Bauk, Y. Cao, A. Henders, K. Y. Chew, D. Gilroy, K. Greaves, L. Labzin, L. Ziser, K. Ronacher, , K. Short

This study identifies trace-level cytokines in PASC patients linked to cardiovascular symptoms and shows their impact on cardiomyocyte function using nanotechnology detection.

bioRxiv · Apr 11, 2024 · PreprintMicrobiology

Spatial ecology and population dynamics of brown trout Salmo trutta L. in reservoirs and headwater tributaries

J. Dodd, R. A. A. Noble, A. D. Nunn, H. M. Owen, P. Moccetti, J. P. Harvey, L. Wallace, B. Gillespie, D. A. Joyce, J. D. Bolland

This study compares spatial ecology and population dynamics of brown trout in reservoirs with and without fish movement barriers, finding that fish passes improve connectivity but have limited overall effectiveness.

bioRxiv · Dec 6, 2023 · PreprintEcology

Single-cell and spatial transcriptomics identify a macrophage population associated with skeletal muscle fibrosis

G. COULIS, D. Jaime, C. Guerrero-Juarez, J. Kastenschmidt, P. Farahat, Q. Nguyen, N. Pervolarakis, K. McLinden, L. Thurlow, S. Movahedi, B. Hughes, J. Duarte, A. Sorn, E. Montoya, I. Mozaffar, , A. Villalta

bioRxiv · Apr 18, 2023Immunology

WDR5 represents a therapeutically exploitable target for cancer stem cells in glioblastoma

K. Mitchell, S. Shakya, S. Arora, S. A. Sprowls, D. J. Silver, C. M. Goins, L. Wallace, G. Roversi, R. Schafer, K. Kay, T. E. Miller, A. Lauko, A. Kashyap, J. D. Kass, E. E. Mulkearns-Hubert, , J. D. Lathia

This study identifies WDR5 as an essential epigenetic regulator in therapy-resistant glioblastoma cancer stem cells and shows that WDR5 inhibitors disrupt CSC maintenance and tumor growth.

bioRxiv · Sep 20, 2021Cancer Biology

Highly multiplexed quantitative phosphosite assay for biology and preclinical studies

H. Keshishian, E. R. McDonald, R. Melanson, D. A. Porter, F. Mundth, K. Krug, L. Wallace, D. Forestier, B. Rabasha, S. E. Marlow, J. Jane-Valbuena, E. Todres, H. Specht, J. Golji, E. Kuhn, , S. A. Carr

The paper introduces SigPath, a mass spectrometry assay that quantifies 284 phosphosites across 200 phosphoproteins, revealing new insights into phospho-signaling in cancer models and human tumors.

bioRxiv · Dec 8, 2020Cancer Biology

Altered lipid metabolism marks glioblastoma stem and non-stem cells in separate tumor niches

S. Shakya, A. Gromovsky, J. Hale, A. Knudsen, B. Prager, L. Wallace, L. O. Penalva, P. Ivanova, H. A. Brown, B. Kristensen, J. Rich, J. Lathia, J. M. Brown, C. G. Hubert

This study identifies distinct lipid metabolism patterns in glioblastoma stem and non-stem cells across different tumor microenvironments, highlighting potential therapeutic targets.

bioRxiv · Sep 20, 2020Cancer Biology

A conserved translation factor is required for optimal synthesis of a membrane protein family in mycobacteria

S. Fishbein, I. D. Wolf, C. L. Dulberger, A. Wang, H. Keshishian, L. Wallace, S. A. Carr, T. R. Ioerger, E. J. Rubin, E. H. Rego

This study identifies LepA as a conserved GTPase that enhances the synthesis of mycobacterial porins, affecting drug tolerance and membrane permeability.

bioRxiv · Dec 11, 2019 · PreprintMicrobiology