Author

C. M. Kerr

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 3

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:host-pathogen & immune response· 3 Organism:mouse· 3 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1 Assay:proteomics· 1 Research Focus:variant calling· 1

Frequent Co-Authors

J. J. O'Connor· 3 shared A. R. Fehr· 2 shared N. Schwarting· 2 shared S. More· 2 shared S. Parthasarathy· 2 shared A. Fehr· 1 shared C. A. Miller· 1 shared D. Chanda· 1 shared

Activity by Year

2021-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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3 shared papersMicrobiology

J. J. O'Connor

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Author profile →

3 papers

Recent·Most cited

MicrobiologybioRxivPreprintJun 16, 2023

PARP12 is required to repress the replication of a Mac1 mutant coronavirus in a cell and tissue specific manner

C. M. Kerr, S. Parthasarathy, N. Schwarting…·A. R. Fehr

This paper shows PARP12 inhibits replication of a Mac1 mutant coronavirus in some cell and tissue types but not all, suggesting other PARPs also contribute to antiviral defense.

DOI 10.1101/2023.06.16.545351

mouseexperimental assay

𝕏 PostBluesky

MicrobiologybioRxivPreprintApr 6, 2023

SARS-CoV-2 Mac1 is required for IFN antagonism and efficient virus replication in mice

Y. M. Alhammad, S. Parthasarathy, R. Ghimire…·A. Fehr

This study shows that SARS-CoV-2 Mac1 is essential for pathogenesis but not replication, as Mac1-deleted virus replicates normally but induces higher IFN responses and reduced disease in mice.

DOI 10.1101/2023.04.06.535927

mouseproteomics

𝕏 PostBluesky

MicrobiologybioRxivPreprintMar 30, 2021

An MHV macrodomain mutant predicted to lack ADP-ribose binding activity is severely attenuated, indicating multiple roles for the macrodomain in coronavirus replication

L. S. Voth, J. J. O'Connor, C. M. Kerr…·A. R. Fehr

This study shows that a MHV macrodomain mutant with reduced ADP-ribose binding is more attenuated than a mutant with reduced hydrolysis, indicating distinct roles for Mac1 functions in coronavirus replication.

DOI 10.1101/2021.03.30.437796

mouseexperimental assay

𝕏 PostBluesky