C. Parent

TGF-β1 activates neutrophil signaling and gene expression but not migration

This study shows TGF-β1 activates neutrophil signaling pathways but not migration, and induces gene expression changes in HL-60 cells.

Simple droplet microfluidics platform for drug screening on cancer spheroids

This paper presents a microfluidics platform for drug screening on cancer spheroids, reducing cell requirements and enabling sequential drug exposure.

Mucosal administration of anti-bacterial antibody provides long-term cross-protection against Pseudomonas aeruginosa respiratory infection

This study shows that mucosal delivery of anti-bacterial antibodies provides rapid pathogen neutralization and long-term cross-protection against secondary Pseudomonas aeruginosa infections.

Ceramide-Rich Microdomains Facilitate Nuclear Envelope Budding during the Biogenesis of LTB4-containing Exosomes

The LTB4-BLT1 signaling axis coordinates actomyosin dynamics and β-2 Integrin trafficking to drive intravascular neutrophil response to infection

This study identifies LTB4-BLT1 signaling and extracellular vesicles as key regulators of neutrophil arrest and extravasation during inflammation.

The evolution of trait variance creates a tension between species diversity and functional diversity

The paper shows that increased species diversity can reduce functional diversity due to evolutionary pressures for narrower trait variation in competitive communities.

A unified model of species abundance, genetic diversity, and functional diversity revealsthe mechanisms structuring ecological communities

The paper introduces a mechanistic model integrating species abundance, genetic diversity, and functional diversity to infer ecological community assembly processes using tropical tree, arthropod, and gastropod communities.