Author

R. Weigert

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 5 Cancer Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 6 Research Focus:cell signaling & trafficking· 5 Organism:mouse· 5 Assay:imaging· 4 Research Focus:cell type annotation· 1 Research Focus:development & morphogenesis· 1 Assay:electronic health records· 1 Organism:human· 1

Frequent Co-Authors

D. Chen· 4 shared A. Shitara· 2 shared S. Ebrahim· 2 shared Y. Ng· 2 shared A. Akhil Shp· 1 shared A. Bhardwaj· 1 shared A. Forrester· 1 shared A. G. Zieman· 1 shared

Activity by Year

2018-2023 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 17 mutual co-author links

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4 shared papersCell Biology

D. Chen

Mutual co-authors in cluster

Author profile →

6 papers

Recent·Most cited

Spatial and Temporal Coordination of Force-generating Actin-based Modules Drives Membrane Remodeling In Vivo

M. Heydecker, A. Shitara, D. Chen, D. Tran, A. Masedunskas, M. Tora, S. Ebrahim, M. A. Appaduray, J. L. Galeano Nino, A. Bhardwaj, K. Narayan, E. C. Hardeman, P. Gunning, R. Weigert

The paper shows how actin filaments dynamically adjust their structure to control membrane transfer between cellular compartments in live rodents.

bioRxiv · Dec 4, 2023 · PreprintCell Biology

Fusion-negative rhabdomyosarcoma orthotopic tongue xenografts for study of invasion, intravasation and metastasis in live animals

S. M. Hammoudeh, Y. Ng, B.-R. Wei, T. Madsen, R. M. Simpson, R. Weigert, P. A. Randazzo

bioRxiv · Sep 21, 2023 · PreprintCancer Biology

Growth factor-induced desialylation for the fast control of endocytosis

E. MacDonald, A. Forrester, C. A. Valades-Cruz, T. D. Madsen, J. Hetmanski, E. Dransart, Y. Ng, R. Godbole, A. Akhil Shp, L. Leconte, V. Chambon, D. Ghosh, A. Pinet, D. D. Bhatia, B. Lombard, , L. Johannes

The paper shows that growth factors induce rapid desialylation of cell surface glycoproteins, enabling reversible changes in glycan structure and function through galectin-mediated endocytosis.

bioRxiv · Sep 12, 2023Cell Biology

The LTB4-BLT1 signaling axis coordinates actomyosin dynamics and β-2 Integrin trafficking to drive intravascular neutrophil response to infection

B. C. Subramanian, N. Melis, D. Chen, W. Wang, D. Gallardo, R. Weigert, C. Parent

This study identifies LTB4-BLT1 signaling and extracellular vesicles as key regulators of neutrophil arrest and extravasation during inflammation.

bioRxiv · Jul 22, 2020Cell Biology

A role for keratins in supporting mitochondrial organization and function in skin keratinocytes

K. Steen, D. Chen, F. Wang, S. Chen, S. Kumar, D. B. Lombard, R. Weigert, A. G. Zieman, C. A. Parent, P. A. Coulombe

This study shows that keratins K6 and K16 regulate mitochondrial structure, function, and dynamics in keratinocytes, contributing to oxidative stress in pachyonychia congenita.

bioRxiv · Mar 10, 2020Cell Biology

Cdc42 negatively regulates endocytosis during apical plasma membrane maintenance and development in mouse tubular organs in vivo

A. Shitara, L. Malec, S. Ebrahim, D. Chen, C. Bleck, M. P. Hoffman, R. Weigert

This study shows that Cdc42 depletion in mice causes apical canaliculi expansion or inhibition, revealing its role in endocytosis regulation during tubular organ development.

bioRxiv · Aug 29, 2018 · PreprintCell Biology