Author

C. Zierhut

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Cell Biology· 1 Microbiology· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Research Focus:cell signaling & trafficking· 2 Approach:experimental assay· 2 Approach:biophysical modeling· 1 Research Focus:cancer & tumor microenvironment· 1 Assay:DNA methylation· 1 Research Focus:drug response / drug discovery· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1

Frequent Co-Authors

H. Funabiki· 2 shared A. Ordureau· 1 shared A. Tan· 1 shared H. Pan· 1 shared J. Z. Xiang· 1 shared L. Deng· 1 shared N. Yang· 1 shared P. Dai· 1 shared

Activity by Year

2017-2021 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersMicrobiology

H. Funabiki

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

MicrobiologybioRxivPreprintOct 25, 2021

Vaccinia E5 is a major inhibitor of the DNA sensor cGAS

N. Yang, Y. Wang, P. Dai…·L. Deng

This study identifies Vaccinia E5 as a major inhibitor of the cGAS-STING pathway by promoting cGAS degradation through proteasome-dependent ubiquitination.

DOI 10.1101/2021.10.25.465197

experimental assayhost-pathogen & immune response

𝕏 PostBluesky

Cell BiologybioRxivJul 25, 2017

The cytoplasmic DNA sensor cGAS promotes mitotic cell death

C. Zierhut, H. Funabiki

This paper shows that cGAS promotes mitotic cell death during prolonged arrest, acting as a guardian against mitotic errors and impacting cell fate in response to anti-mitotic drugs.

DOI 10.1016/j.cell.2019.05.035

humanproteomics

𝕏 PostBluesky