Safety assessment of insecticidal proteins: A case study utilizing His-tagged protein to determine the safety of Mpp75Aa1.1, a new ETX_MTX2 protein that controls western corn rootworm
C. Wang, G. J. Bean, C. J. Chen, C. R. Kessenich, J. Peng, N. R. Visconti, J. S. Milligan, R. G. Moore, J. Tan, T. c. Edrington, B. Li, K. S. Giddings, D. Bowen, J. Luo, T. Ciche, W. J. Moar
This paper assesses the safety of the insecticidal protein Mpp75Aa1.1 by evaluating its allergenicity, toxicity, and degradation properties using purified and His-tagged variants.
bioRxiv · Mar 28, 2022 · PreprintPharmacology & Toxicology