The neonatal Fc receptor and DPP4 are human astrovirus receptors
H. Ingle, J. M. Molleston, P. D. Hall, D. Bui, L. Wang, L. Foster, A. Antia, S. Ding, S. Lee, D. H. Fremont, M. T. Baldridge
This study identifies FcRn and DPP4 as human astrovirus receptors and shows that targeting these factors with existing inhibitors prevents infection in human enteroid cultures.
bioRxiv · Jul 12, 2024 · PreprintMicrobiology