Author

D. Fitzgerald

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 2 Cancer Biology· 2 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Research Focus:cell type annotation· 3 Organism:human· 3 Research Focus:host-pathogen & immune response· 2 Assay:scRNA-seq· 2 Assay:spatial transcriptomics· 2 Research Focus:cell-cell communication· 1 Assay:ChIP-seq· 1

Frequent Co-Authors

C. Schaffitzel· 2 shared C. Toelzer· 2 shared F. Czernilofsky· 2 shared F. Garzoni· 2 shared G. P. Nolan· 2 shared H. Voehringer· 2 shared I. Berger· 2 shared K. Gupta· 2 shared

Activity by Year

2020-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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2 shared papersBiochemistry

C. Schaffitzel

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

Multimodal and spatially resolved profiling identifies distinct patterns of T-cell infiltration in nodal B-cell lymphoma entities

T. Roider, M. A. Baertsch, D. Fitzgerald, H. Voehringer, B. J. Brinkmann, F. Czernilofsky, M. Knoll, L. Llao-Cid, P.-M. Bruch, N. Liebers, C. M. Schuerch, V. Passerini, A. Brobeil, G. Mechtersheimer, C. Mueller-Tidow, , S. Dietrich

Nature Cell Biology · Mar 1, 2024Peer-reviewedCancer Biology

A single-cell multi-omic and spatial atlas of B cell lymphomas reveals differentiation drives intratumor heterogeneity

D. Fitzgerald, T. Roider, M. A. Baertsch, A. Kibler, A. Horlova, E. K. Chung, H. Voehringer, A. Mathioudaki, B. Budeus, V. Passerini, M. Knoll, J. Mammen, L. Li, L. Caille, F. Czernilofsky, , W. Huber

This study reveals that cellular differentiation drives intratumor heterogeneity in B-cell lymphomas, with distinct maturation states associated with different survival outcomes.

bioRxiv · Nov 6, 2023 · PreprintCancer Biology

Genome-wide mapping of the Escherichia coli PhoB regulon reveals many transcriptionally inert, intragenic binding sites

D. Fitzgerald, A. M. Stringer, C. Smith, P. Lapierre, J. T. Wade

This study maps the PhoB regulon in E. coli and finds that most binding sites are intragenic and not associated with transcription regulation or conservation.

bioRxiv · Feb 7, 2023 · PreprintMicrobiology

The Free Fatty Acid-Binding Pocket is a Conserved Hallmark in Pathogenic β-Coronavirus Spike Proteins from SARS-CoV to Omicron

C. Toelzer, K. Gupta, S. K. N. Yadav, L. Hodgson, M. Kavanagh Williamson, D. Buzas, U. Borucu, K. Powers, R. Stenner, K. Vasileiou, F. Garzoni, D. Fitzgerald, C. Payre, G. Lambeau, A. D. Davidson, , C. Schaffitzel

The paper identifies a conserved free fatty acid-binding pocket in pathogenic β-coronavirus spike proteins that suppresses viral infection and replication.

bioRxiv · Apr 22, 2022Biochemistry

Unexpected free fatty acid binding pocket in the cryo-EM structure of SARS-CoV-2 spike protein

C. Toelzer, K. Gupta, S. K. Yadav, U. Borucu, F. Garzoni, O. Staufer, J. Capin, J. Spatz, D. Fitzgerald, I. Berger, C. Schaffitzel

The paper reveals a direct structural link between SARS-CoV-2 spike protein and linoleic acid, a key molecule in inflammation, immune modulation, and membrane fluidity.

bioRxiv · Jun 18, 2020Biochemistry