A genetic basis for cancer sex differences revealed in Xp11 translocation renal cell carcinoma
M. Achom, A. Sadagopan, C. Bao, F. McBride, Q. Xu, P. Konda, R. W. Tourdot, J. Li, M. Nakhoul, D. Gallant, U. A. Ahmed, J. O'Toole, D. Freeman, G.-S. M. Lee, J. Hecht, , S. R. Viswanathan
This study identifies a genetic basis for cancer sex differences in Xp11 translocation renal cell carcinoma by showing a 2:1 female:male ratio in TFE3 fusions involving the inactive X chromosome.
bioRxiv · Aug 4, 2023 · PreprintCancer Biology