C. Tran

Triglyceride Polygenic Score Identifies Differential Bleeding and Cardiovascular Risk with Aspirin in Primary Prevention

This paper finds that a triglyceride-related polygenic score modifies aspirin's effects on bleeding and cardiovascular events in older adults, with different outcomes based on genetic risk profiles.

Intermittent hypoxia therapy engages multiple longevity pathways to double lifespan in C.elegans

This study shows intermittent hypoxia therapy doubles C. elegans lifespan without HIF-1 but requires DAF-16/FOXO and other phosphatidylinositol signaling components.

The origin and dynamics of cellular heterogeneity vary across lineage subtypes of castrate resistant prostate cancer

This study examines the origin and dynamics of cellular heterogeneity in different subtypes of castrate-resistant prostate cancer using patient-derived organoids and single-cell analyses, identifying distinct lineage plasticity patterns and therapeutic targets.

Local activation of focal adhesion kinase orchestrates the positioning of presynaptic scaffold proteins and Ca2+ channel function to control glucose dependent insulin secretion.

The paper shows local activation of focal adhesion kinase at the β cell capillary interface regulates presynaptic scaffold proteins and Ca2+ channel function to control glucose-dependent insulin secretion.

Defining the Caprin-1 interactome in unstressed and stressed conditions

The paper identifies the Caprin-1 interactome under unstressed and stressed conditions, revealing novel components of stress granules and their association with ALS aggregates.

Isolation and characterization of Streptomyces bacteriophages and Streptomyces strains encoding biosynthetic arsenals

This study identifies novel Streptomyces strains and phages with potential for antibiotic discovery and genetic manipulation.

CRK2 enhances salt tolerance by regulating callose deposition in connection with PLDα1

The paper shows CRK2 enhances salt tolerance in Arabidopsis by regulating endocytosis and callose deposition, working with PLDα1.

Live imaging of Aiptasia larvae, a model system for studying coral bleaching, using a simple microfluidic device

This paper introduces a microfluidic device to image live Aiptasia larvae and their algal symbionts under environmental stress, observing algal expulsion as a potential mechanism of coral bleaching.