Cancer BiologybioRxiv
Metabolic reprogramming of cancer cells by JMJD6-mediated pre-mRNA splicing is associated with therapeutic response to splicing inhibitor
J. YANG, C. M. Jablonowski, W. Quarni…·G. Wu
This study shows JMJD6 links pre-mRNA splicing and metabolism in MYC-driven cancers, and its inhibition enhances therapeutic response to splicing inhibitors.
DOI 10.7554/elife.90993