Author

D. Hoyos

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2

Signature Assays, Organisms & Methods

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Organism:human· 2 Approach:statistical model· 2 Assay:whole-genome sequencing· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:differential expression· 1

Frequent Co-Authors

A. Solovyov· 2 shared B. D. Greenbaum· 2 shared A. D. Gioacchino· 1 shared A. Karacay· 1 shared A. W. Drong· 1 shared C. A. Iacobuzio-Donahue· 1 shared C. Chu· 1 shared D. D. Carvalho· 1 shared

Activity by Year

2023-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 30 mutual co-author links

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2 shared papersCancer Biology

A. Solovyov

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Author profile →

2 papers

Recent·Most cited

Cancer cells co-evolve with retrotransposons to mitigate viral mimicry

S. Sun, J. Hong, E. You, K. M. Tsanov, J. Chacon-Barahona, A. D. Gioacchino, D. Hoyos, H. Li, H. Jiang, H. Ly, S. A. Marhon, R. Murali, P. Chanda, A. Karacay, N. Vabret, , B. D. Greenbaum

This study shows pancreatic tumors co-evolve with retrotransposons to modulate immune responses by regulating viral mimicry through SINEs and L1 retrotransposition.

bioRxiv · May 19, 2023 · PreprintCancer Biology

Mechanism-guided quantification of LINE-1 reveals p53 regulation of both retrotransposition and transcription

A. Solovyov, J. M. Behr, D. Hoyos, E. M. Banks, A. W. Drong, J. Z. Zhong, E. Garcia-Rivera, W. McKerrow, C. Chu, D. M. Zaller, M. Fromer, B. D. Greenbaum

This study quantifies LINE-1 retrotransposition and expression in cancer, showing TP53 mutations enable retrotransposition by disinhibiting L1 expression and enabling reintegration.

bioRxiv · May 11, 2023 · PreprintCancer Biology