K. Rao

Myoglobin promotes cardiomyocyte differentiation through oxidatively modulating the Hippo Kinase Pathway

This study shows myoglobin promotes cardiomyocyte differentiation by modulating the Hippo pathway through oxidative regulation of LATS1 and YAP.

Measurement of Klebsiella Intestinal Colonization Density to Assess Infection Risk

This study develops a qPCR assay to measure Klebsiella colonization density in rectal swabs and finds that higher density is significantly associated with increased infection risk.

Gut microbiome features are associated with sepsis onset and outcomes

This study finds that gut microbiome features, including increased Enterococcus and total bacterial abundance, and decreased butyrate-producing bacteria, are associated with sepsis onset and mortality.

DIFFERENTIAL BIOENERGETICS IN ADULT RAT CARDIOMYOCYTES ISOLATED FROM THE RIGHT VERSUS LEFT VENTRICLE

The paper compares bioenergetics in adult rat cardiomyocytes from the right and left ventricle, finding greater maximal respiration and glycolytic rate in right ventricle cells.

Control of cytokinesis by β-adrenergic receptors indicates an approach for regulating cardiomyocyte endowment

This study shows that β-adrenergic receptor signaling regulates cardiomyocyte cytokinesis, and β-blockers like propranolol can enhance division in ToF/PS cardiomyocytes, potentially improving heart function in CHD patients.

Temporal Gut Microbial Changes Predict Recurrent Clostridium difficile in Patients with and without Ulcerative Colitis

The paper identifies microbial features predicting recurrent Clostridium difficile infection in UC patients and non-UC individuals using 16S rRNA sequencing and logistic regression models.

Inter-individual Recovery Of The Microbiota And Metabolome Over Time Following Fecal Microbiota Transplantation In Patients With Recurrent Clostridium difficile Infection

This study examines microbiota and metabolome recovery in patients with recurrent CDI after FMT, identifying microbial associations with metabolite changes and individualized recovery patterns.