M. Islam

Highly accurate metagenome-assembled genomes from human gut microbiota using long-read assembly, binning, and consolidation methods

This study improves metagenome-assembled genomes from human gut microbiota using long-read sequencing and novel assembly methods, yielding more high-quality MAGs and uncovering uncultured diversity.

A dynamin-like protein in the human malaria parasite plays an essential role in mitochondrial homeostasis and fission during asexual blood stages

This study identifies PfDyn2, a dynamin-like protein in P. falciparum, essential for mitochondrial fission and homeostasis during asexual blood stages of malaria.

Combination of AID2 and BromoTag expands the utility of degron-based protein knockdowns

The paper combines AID2 and BromoTag degron systems to enhance protein depletion, demonstrating their effectiveness in suppressing DNA replication by co-depleting ORC1 and CDC6.

The interplay between dormant mutated cells and tumor promotion by chronic tissue damage in determining cancer risk.

This study analyzes mouse skin tumors to determine how environmental factors like TPA, obesity, and wounding affect mutational burden and cancer risk, finding that tumor promoters, not mutation number, limit tumor growth.

Epigenetic mediated functional reprogramming of immune cells leads to HBsAg seroconversion in Hepatitis B Virus Reactivation patients

This study identifies epigenetic changes in HBV reactivation patients that drive immune and metabolic reprogramming, leading to HBsAg seroconversion.

A resurrection ecology test for the effects of ionizing radiation and other environmental correlates on Daphnia evolution

The paper describes a resurrection ecology study of Daphnia eggs from Utah lakes exposed to nuclear fallout, but failed to hatch eggs for life history experiments, instead sharing data and methods for future research.

A Machine Learning Approach to Predict Cellular Mechanical Stresses in Response to Chemical Perturbation

This paper uses machine learning to predict cellular mechanical stresses from chemical perturbations, finding QSVM best predicts intercellular stresses and SLR best predicts tractions.

Phytochemical and antibacterial analyses of Onychium japonicum (Thunb.) Kunze.

This study investigates the phytochemical composition and antibacterial potential of Onychium japonicum, finding it rich in bioactive compounds and active against multidrug-resistant bacteria.

Strategies for enriching and characterizing proteins with inhibitory properties on the yeast surface

This paper develops strategies to discover and characterize inhibitory antibodies using yeast display, showing that IC50 values can be measured directly on the yeast surface.

Efficacy of plasmid-encoded CRISPR-Cas antimicrobial is affected by competitive factors found in wild Enterococcus faecalis isolates

This study evaluates the effectiveness of CRISPR-Cas antimicrobials against wild E. faecalis isolates and finds that competitive factors in these isolates reduce CRISPR-Cas efficacy.

Genetically distant bacteriophages elicit unique genomic changes in Enterococcus faecalis

This study shows that genetically distinct bacteriophages induce unique genomic changes in Enterococcus faecalis, highlighting phage-specific host responses during evolution.

Human engineered skeletal muscle of hypaxial origin from pluripotent stem cells with advanced function and regenerative capacity

This study develops a human hypaxial muscle model from pluripotent stem cells with functional maturation and regenerative capacity for studying muscle biology and disease.

TRAF2, an innate immune sensor, reciprocally regulates mitophagy and inflammation to maintain cardiac myocyte homeostasis.

This study shows TRAF2 regulates mitophagy and inflammation in cardiac myocytes to prevent cell death and maintain homeostasis.

Role of African swine fever virus (ASFV) proteins EP153R and EP402R in reducing viral persistence and virulence from attenuated BeninΔDP148R

This study investigates the role of ASFV proteins EP153R and EP402R in viral persistence and virulence by deleting them from an attenuated virus, showing that EP402R deletion reduces persistence while EP153R deletion alone has limited effect.

Concept design of a bionic grasp to capture the hand motion

This paper designs a low-cost smart glove for hand exercise in stroke rehabilitation, which can capture motion data and transfer it to an application.

Vancomycin resistance in Enterococcus faecium from the Dallas, Texas area is conferred predominantly on pRUM-like plasmids

This study analyzes VREfm genomes from Dallas, Texas, finding that pRUM-like plasmids are the primary vehicle for vancomycin resistance.

Detour learning ability and the effect of novel sensory cues on learning in Australian bull ants, Myrmecia midas

This study investigates detour learning in Australian bull ants, finding that they learn new routes around barriers without relying on barrier cues, but their navigation is disrupted by novel sensory cues.

Comprehensive studies of Head Maralla, Punjab, Pakistan vegetation for ethnopharmacological and ethnobotanical uses and their elaboration through quantitative indices

This study examines the ethnobotanical and ethnopharmacological uses of vegetation in Head Maralla, Punjab, Pakistan, identifying species and habitats for conservation.

ddcP, pstB, and excess D-lactate impact synergism between vancomycin and chlorhexidine against Enterococcus faecium 1,231,410

This study identifies genetic factors and environmental conditions that affect the synergistic effect of chlorhexidine and vancomycin against VanA-type Enterococcus faecium.

Activation of SnRK2 by the Raf-like kinase ARK represents a common mechanism of ABA response in embryophytes

The paper identifies Ser1029 phosphorylation as critical for ARK activation in ABA response, showing its role in SnRK2 regulation and stress tolerance in moss.

WRN Helicase is a Synthetic Lethal Target in Microsatellite Unstable Cancers

The paper identifies WRN helicase as a synthetic lethal target in microsatellite unstable cancers through CRISPR/Cas9 and RNAi screens, showing its essentiality in MSI cell lines.