D. MacLean

The blast effector Pwl2 is a virulence factor that modifies the cellular localisation of host protein HIPP43 to suppress immunity.

This study identifies Pwl2 as a virulence factor in the rice blast fungus that suppresses host immunity by altering the localization of HIPP43.

The phosphorylation landscape of infection-related development by the rice blast fungus

This study maps the phosphorylation landscape of the rice blast fungus during infection, identifying key phosphoproteins and pathways involved in disease progression.

Innate immune receptor C5aR1 regulates cancer cell fate and can be targeted to improve radiotherapy in tumours with immunosuppressive microenvironments

This study identifies C5aR1 as a targetable receptor on cancer cells that enhances radiotherapy efficacy in immunosuppressive tumours by promoting apoptosis without affecting normal tissues.

The transcriptional landscape of plant infection by the rice blast fungus Magnaporthe oryzae reveals distinct families of temporally co-regulated and structurally conserved effectors

An improved assembly of the Albugo candida Ac2V genome reveals the expansion of the "CCG" class of effectors

The paper improves the genome assembly of Albugo candida Ac2V and identifies a 250% expansion in the CCG effector class.

Chromatin accessibility landscapes activated by cell surface and intracellular immune receptors

The paper uses RNA-seq and ATAC-seq to show that both SRMI and IRMI increase chromatin accessibility at defense genes, revealing overlapping transcriptional regulatory mechanisms.

High-resolution Expression Profiling of Selected Gene Sets during Plant Immune Activation

The paper develops a method to assess differential gene expression of selected genes during plant immune activation using sequence capture and RNA-seq.

An Oomycete Effector Protein Induces Shade Avoidance In Arabidopsis And Attenuates Salicylate Signaling By Binding To Host Proteins Of The RADICAL-INDUCED CELL DEATH1 Family

The paper shows that the oomycete effector HaRxL106 induces shade avoidance and suppresses salicylic acid signaling in Arabidopsis by interacting with RCD1, a protein involved in immune responses.