P. Ding

The m6A Reader ECT1 Mediates Seed Germination via the DAG2-ECT1-PHYB Regulatory Cascade in Arabidopsis

This study identifies ECT1 as an m6A reader protein that promotes seed germination in Arabidopsis through a DAG2-ECT1-PHYB regulatory cascade involving transcriptional and post-transcriptional control.

Habitat fragmentation mediates the mechanisms underlying long-term climate-driven thermophilization in birds

The paper examines how habitat fragmentation influences climate-driven changes in bird communities over time, finding that fragmentation affects colonization and extinction rates of warm- and cold-adapted species.

Modular mechanisms of immune priming and growth inhibition mediated by plant effector-triggered immunity

This study identifies two distinct signalling modules in Arabidopsis that mediate different aspects of effector-triggered immunity, with implications for improving disease resistance in crops.

Implantable nanophotonic neural probes for integrated patterned photostimulation and electrophysiology recording

This paper introduces implantable nanophotonic neural probes that enable patterned photostimulation and electrophysiology recording with minimal thermal damage.

Cell type-specific responses to fungal infection in plants revealed by single-cell transcriptomics

This study uses single-cell transcriptomics to reveal cell type-specific responses to fungal infection in Arabidopsis thaliana, identifying gene expression patterns and defense mechanisms.

Multi-omics analyses of single cell-derived colorectal cancer organoids reveal intratumor heterogeneity and immune response diversity

Osteocytes regulate organismal senescence of bone and bone marrow

This study shows that osteocyte ablation in mice leads to senescence-associated changes in bone and bone marrow lineages, causing sarcopenia, osteoporosis, and shortened lifespan.

Molecular mechanisms governing circulating immune cell heterogeneity across different species revealed by single cell sequencing

This study uses single-cell RNA-sequencing to analyze immune cell diversity across 12 species, revealing conserved and divergent molecular mechanisms and cellular interactions.

Screening of cell-virus, cell-cell, gene-gene interactions among kingdoms of life at single cell resolution

The paper screens cell-virus and cell-cell interactions across multiple species to identify potential hosts and co-evolution patterns of viruses including SARS-CoV-2.

Perception of structurally distinct effectors by the integrated WRKY domain of a plant immune receptor.

This paper reveals how the WRKY domain of the Arabidopsis NLR receptor RRS1 recognizes structurally distinct bacterial effectors to initiate immunity.

Viral receptor profiles of masked palm civet revealed by single-cell transcriptomics

The paper uses single-cell transcriptomics to profile viral receptor expression in masked palm civets, identifying potential tissue tropisms for 132 viruses.

The compound of baicalein, wogonin, and oroxylin-A inhibits EMT in A549 cell line via PI3K/AKT-TWIST1-glycolysis pathway

This study identifies baicalein, wogonin, and oroxylin-A as active compounds in TFAE that inhibit EMT in A549 cells via the PI3K/AKT-TWIST1-glycolysis pathway.

Chromatin accessibility landscapes activated by cell surface and intracellular immune receptors

The paper uses RNA-seq and ATAC-seq to show that both SRMI and IRMI increase chromatin accessibility at defense genes, revealing overlapping transcriptional regulatory mechanisms.

Single-cell screening of SARS-CoV-2 target cells in pets, livestock, poultry and wildlife

The paper screens SARS-CoV-2 target cells across 11 animal species using single-cell transcriptomes, finding higher proportions in cats and detecting them in multiple pig cell types.

Kidney single-cell atlas reveals myeloid heterogeneity in progression and regression of kidney disease.

The paper uses scRNA-seq to study kidney disease progression and regression, identifying new myeloid cell subtypes and their roles in injury and repair.

Mutual Potentiation of Plant Immunity by Cell-surface and Intracellular Receptors

This study shows that plant immune pathways activated by cell-surface and intracellular receptors mutually enhance each other to provide effective resistance against pathogens.

High-resolution Expression Profiling of Selected Gene Sets during Plant Immune Activation

The paper develops a method to assess differential gene expression of selected genes during plant immune activation using sequence capture and RNA-seq.

Estradiol-inducible AvrRps4 expression reveals distinct properties of TIR-NLR-mediated effector-triggered immunity

The paper induces AvrRps4 expression in Arabidopsis to study RRS1/RPS4-mediated immunity without pathogen presence, revealing downstream immune responses.

PI3K/AKT inhibition in tumor propagating cells of DLBCL reverses R-CHOP resistance by destabilizing SOX2

Single cell RNA-seq reveals cellular diversity and developmental characteristics of human infant retina

This study uses single-cell RNA-seq to analyze human infant retina, identifying cell types, communication networks, and developmental changes, providing a resource for retinal research and regenerative medicine.

Aerobic removal of microcystin-LR by a novel native effective bacterial community designated as YFMCD4 isolated from Lake Taihu

This study identifies a bacterial community YFMCD4 that effectively removes microcystin-LR from water, with degradation rates influenced by temperature, pH, and concentration.