Author

D. Oxley

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 2 Cell Biology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Assay:proteomics· 4 Research Focus:cell type annotation· 2 Organism:human· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:clustering· 1 Approach:deep learning· 1

Frequent Co-Authors

H. Okkenhaug· 2 shared S. Walker· 2 shared A. Anwar· 1 shared A. F. Lopez-Clavijo· 1 shared A. H. Lystad· 1 shared A. Kielkowska· 1 shared A. Segonds-Pichon· 1 shared A. Simonsen· 1 shared

Activity by Year

2020-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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2 shared papersBiochemistry

H. Okkenhaug

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

A cyclic peptide toolkit reveals mechanistic principles of peptidylarginine deiminase IV (PADI4) regulation

M. T. Bertran, R. Walmsley, T. F. M. Cummings, I. Aramburu, D. J. Benton, J. Assalaarachchi, M. Chasampalioti, T. Swanton, D. Joshi, S. Federico, H. Okkenhaug, L. Yu, D. Oxley, S. Walker, V. Papayannopoulos, , L. J. Walport

The paper develops cyclic peptide modulators of PADI4 and reveals their mechanism of action and cellular activity.

bioRxiv · Dec 12, 2023Biochemistry

PLEKHS1 drives PI3Ks and remodels pathway homeostasis in PTEN-null prostate

T. A. M. Chessa, P. Jung, S. Suire, A. Anwar, K. E. Anderson, D. Barneda, A. Kielkowska, B. A. Sadiq, D. Oxley, S. Felisbino, D. Spensberger, A. Segonds-Pichon, M. Wilson, S. Walker, H. Okkenhaug, , L. R. Stephens

The paper identifies PLEKHS1 as a driver of PI3K activity in PTEN-null prostate tissue, showing it bypasses feedback mechanisms to promote tumour progression.

bioRxiv · May 18, 2023Cell Biology

Solvent Precipitation SP3 (SP4) enhances recovery for proteomics sample preparation without magnetic beads

H. E. Johnston, K. Yadav, J. M. Kirkpatrick, G. S. Biggs, D. Oxley, H. B. Kramer, R. S. Samant

This paper introduces SP4, a proteomics sample preparation method that replaces magnetic beads with solvent precipitation and centrifugation, improving protein recovery and reproducibility compared to SP3.

bioRxiv · Sep 24, 2021Biochemistry

Non-canonical autophagy drives alternative ATG8 conjugation to phosphatidylserine

J. Durgan, A. H. Lystad, K. Sloan, S. R. Carlsson, M. I. Wilson, E. Marcassa, R. Ulferts, J. Webster, A. F. Lopez-Clavijo, M. J. Wakelam, R. Beale, A. Simonsen, D. Oxley, O. Florey

This study shows that during non-canonical autophagy, ATG8 proteins are conjugated to phosphatidylserine instead of phosphatidylethanolamine, revealing a distinct lipidation mechanism.

bioRxiv · May 14, 2020Cell Biology