Author

T. Swanton

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Approach:deep learning· 1 Research Focus:drug response / drug discovery· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Assay:proteomics· 1

Frequent Co-Authors

A. D. Adamson· 1 shared C. Lawrence· 1 shared D. Brough· 1 shared D. J. Benton· 1 shared D. Joshi· 1 shared D. Oxley· 1 shared H. Okkenhaug· 1 shared H. Suga· 1 shared

Activity by Year

2020-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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1 shared paperImmunology

A. D. Adamson

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2 papers

Recent·Most cited

A cyclic peptide toolkit reveals mechanistic principles of peptidylarginine deiminase IV (PADI4) regulation

M. T. Bertran, R. Walmsley, T. F. M. Cummings, I. Aramburu, D. J. Benton, J. Assalaarachchi, M. Chasampalioti, T. Swanton, D. Joshi, S. Federico, H. Okkenhaug, L. Yu, D. Oxley, S. Walker, V. Papayannopoulos, , L. J. Walport

The paper develops cyclic peptide modulators of PADI4 and reveals their mechanism of action and cellular activity.

bioRxiv · Dec 12, 2023Biochemistry

LRRC8A regulates hypotonicity-induced NLRP3 inflammasome activation

J. P. Green, T. Swanton, L. V. Morris, L. Y. El-Sharkawy, J. Cook, S. Yu, J. Beswick, A. D. Adamson, N. E. Humphreys, R. Bryce, S. Freeman, C. Lawrence, D. Brough

This study identifies LRRC8A as a key regulator of hypotonicity-induced NLRP3 inflammasome activation, distinct from DAMP-induced activation.

bioRxiv · Jun 11, 2020Immunology