Author

K. Sloan

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1 Cell Biology· 1 Microbiology· 1 Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Research Focus:cell type annotation· 2 Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:drug response / drug discovery· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

A. Akinc· 1 shared A. B. Castoreno· 1 shared A. F. Lopez-Clavijo· 1 shared A. H. Lystad· 1 shared A. Kasper· 1 shared A. Rogers· 1 shared A. Sahakyan· 1 shared A. Sherry· 1 shared

Activity by Year

2020-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 18 mutual co-author links

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Curved chords = mutual co-authorship

1 shared paperPharmacology & Toxicology

A. Akinc

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Robust and durable prophylactic protection conferred by RNA interference in preclinical models of SARS-CoV-2

Y. I. Anglero-Rodriguez, F. A. Lempp, J. McIninch, M. K. Schlegel, C. R. Brown, D. J. Foster, A. B. Castoreno, T. Nguyen, M. Subramanian, M. Montiel-Ruiz, H. Kaiser, A. Sahakyan, R. Spreafico, S. S. Morskaya, J. D. Barry, , V. Jadhav

This study identifies two siRNA combinations that provide robust prophylactic protection against SARS-CoV-2 in hamsters by reducing viral load and preventing lung pathology.

bioRxiv · Mar 20, 2022 · PreprintPharmacology & Toxicology

Extremely thermophilic endospores germinate and metabolise organic carbon in sediments heated to above 80°C

E. Bell, J. E. Rattray, K. Sloan, A. Sherry, G. Pilloni, C. R. Hubert

bioRxiv · Oct 10, 2021Microbiology

Dynamic regulation of hierarchical heterogeneity in Acute Myeloid Leukemia serves as a tumor immunoevasion mechanism

C. Pospori, W. Grey, S. Gonzalez-Anton, S. V. Gibson, C. Georgiou, F. Birch, G. Stevens, T. Williams, R. Khorshed, M. L. R. Haltalli, M.-N. Skoufou-Papoutsaki, K. Sloan, H. H. Encabo, J. Hopkins, C. Christodoulidou, , C. L. Lo Celso

The paper shows that hierarchical heterogeneity in AML cells, regulated by immune responses, contributes to disease progression through PDL1 upregulation and dynamic balance between proliferation and immunosuppression.

bioRxiv · Dec 21, 2020 · PreprintCancer Biology

Non-canonical autophagy drives alternative ATG8 conjugation to phosphatidylserine

J. Durgan, A. H. Lystad, K. Sloan, S. R. Carlsson, M. I. Wilson, E. Marcassa, R. Ulferts, J. Webster, A. F. Lopez-Clavijo, M. J. Wakelam, R. Beale, A. Simonsen, D. Oxley, O. Florey

This study shows that during non-canonical autophagy, ATG8 proteins are conjugated to phosphatidylserine instead of phosphatidylethanolamine, revealing a distinct lipidation mechanism.

bioRxiv · May 14, 2020Cell Biology