Author

D. Pellman

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Cancer Biology· 2 Cell Biology· 2 Biophysics· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Research Focus:chromatin & epigenetic regulation· 4 Approach:experimental assay· 4 Organism:human· 4 Research Focus:cancer & tumor microenvironment· 2 Research Focus:cell signaling & trafficking· 2 Assay:imaging· 2 Approach:mechanistic / dynamical model· 2 Research Focus:cell type annotation· 1

Frequent Co-Authors

A. Spektor· 2 shared C.-Z. Zhang· 2 shared E. Stokasimov· 2 shared S. Liu· 2 shared A. E. Leschziner· 1 shared A. Khodjakov· 1 shared A. M. Cheng· 1 shared B. Cheng· 1 shared

Activity by Year

2018-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 14 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersCancer Biology

A. Spektor

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

2D and 3D multiplexed subcellular profiling of nuclear instability in human cancer

S. Coy, B. Cheng, J. S. Lee, R. Rashid, L. Browning, Y. Xu, S. S. Chakrabarty, C. Yapp, S. Chan, J. B. Tefft, A. Spektor, K. L. Ligon, G. J. Baker, D. Pellman, P. K. Sorger, S. Santagata

The paper shows nuclear rupture is common in cancer, especially glioblastoma, and links it to lamin proteins and immune signaling.

bioRxiv · Nov 7, 2023 · PreprintCancer Biology

Transgenerational transcriptional heterogeneity from cytoplasmic chromatin

S. Papathanasiou, N. A. Mynhier, S. Liu, E. Jacob, E. Stokasimov, B. van Steensel, C.-Z. Zhang, D. Pellman

This study shows that micronuclei can cause heritable transcriptional changes by disrupting chromatin states, even after chromosomes are reincorporated into normal nuclei.

bioRxiv · Jan 12, 2022 · PreprintCell Biology

Multimodal tubulin binding by the yeast kinesin-8, Kip3, underlies its motility and depolymerization

H. Arellano-Santoyo, R. A. Hernandez-Lopez, E. Stokasimov, R. Y. Wang, D. Pellman, A. E. Leschziner

This study identifies structural features of yeast kinesin-8 Kip3 that enable its switch between motility and MT depolymerization through cryo-EM and molecular dynamics simulations.

bioRxiv · Oct 12, 2021 · PreprintBiophysics

Mechanisms Generating Cancer Genome Complexity From A Single Cell Division Error

N. Umbreit, C.-Z. Zhang, L. D. Lynch, L. J. Blaine, A. M. Cheng, R. W. Tourdot, L. Sun, H. F. Almubarak, K. Judge, T. J. Mitchell, A. Spektor, D. Pellman

This study identifies a mutational cascade triggered by chromosome bridge formation that leads to chromothripsis and contributes to cancer genome complexity and sub-clonal heterogeneity.

bioRxiv · Nov 7, 2019Cancer Biology

Nuclear envelope assembly defects link mitotic errors to chromothripsis

S. Liu, M. Kwon, M. Mannino, N. Yang, A. Khodjakov, D. Pellman

This study shows that defective nuclear envelope assembly in micronuclei leads to chromothripsis by impairing nuclear import and genome integrity.

bioRxiv · Feb 11, 2018Cell Biology