M. Kwon

Dual-mode action of scalable, high-quality engineered stem cell-derived SIRPα-extracellular vesicles for treating acute liver failure

This paper develops SIRPα-expressing extracellular vesicles from engineered stem cells to treat acute liver failure by resolving necroptosis and promoting liver regeneration, showing reduced liver damage and improved survival in models.

Genome-wide exploration of metabolic-based pyrethroid resistance mechanism in Helicoverpa armigera

This study identifies CYP3 subfamily gene variants and differential expression of detoxification enzymes as key factors in deltamethrin resistance in Helicoverpa armigera, rather than target site mutations.

Co-Delivery of Synergistic Antimicrobials with Polyelectrolyte Nanocomplexes to Treat Bacterial Biofilms and Lung Infections

This study develops AgTob-NCs, polyelectrolyte nanocomplexes co-delivering tobramycin and silver nanoparticles, showing synergistic antimicrobial activity against Pseudomonas aeruginosa biofilms and improving lung infection outcomes in mice.

Extracellular vesicle molecular signatures characterize metastatic dynamicity in ovarian cancer

This study identifies a 7-gene extracellular vesicle signature associated with ovarian cancer metastasis but lacks a definitive signature due to limited sample size.

Development of a species diagnostic molecular tool for an invasive pest, Mythimna loreyi using LAMP

This paper develops a LAMP assay for rapid identification of the invasive pest Mythimna loreyi using a species-specific sequence from the NADH dehydrogenase subunit 5 gene.

Development of a diamide resistance diagnostic method using LAMP based on a resistance-specific indel in ryanodine receptors for Spodoptera exigua (Lepidoptera: Noctuidae)

Physiological characterization of nitrate ammonifying bacteria isolated from rice paddy soils via a newly developed high-throughput screening method

This paper isolates and characterizes DNRA bacteria from rice paddy soils using a new high-throughput method, revealing a link between NO3- repression and C-to-N ratio regulation of DNRA activity.

Development of a simple and accurate molecular tool for Spodoptera frugiperda species identification using LAMP

This paper develops a LAMP assay for rapid and accurate identification of Spodoptera frugiperda using a specific mtDNA region, showing high sensitivity and simplicity.

Characterization of cis-prenyltransferase complexes in guayule (Parthenium argentatum), an alternative natural rubber-producing plant

This study identifies and characterizes cis-prenyltransferase (CPT) and CPT-binding protein (CBP) complexes in guayule, showing their role in natural rubber biosynthesis.

Nuclear envelope assembly defects link mitotic errors to chromothripsis

This study shows that defective nuclear envelope assembly in micronuclei leads to chromothripsis by impairing nuclear import and genome integrity.