ImmunologybioRxivPreprint
Correction of age-associated defects in dendritic cell functions enables CD4+ T cells to eradicate tumors in the elderly
D. Zhivaki, F. Borriello, S. Kennedy…·J. C. Kagan
This study shows that CD4+ T cells, supported by hyperactivator-stimulated dendritic cells, can eliminate tumors in elderly mice, suggesting a strategy to correct age-related immune defects.