Author

E. A. Franzosa

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 2 Microbiology· 2

Signature Assays, Organisms & Methods

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Assay:metagenomics· 4 Research Focus:differential expression· 3 Organism:human· 3 Approach:statistical model· 3 Approach:deep learning· 2 Approach:experimental assay· 2 Research Focus:gene regulatory network inference· 2 Research Focus:host-pathogen & immune response· 2

Frequent Co-Authors

C. Huttenhower· 4 shared Y. Zhang· 4 shared A. S. Devlin· 2 shared G. Weingart· 2 shared J. R. Huh· 2 shared L. J. McIver· 2 shared L. Yao· 2 shared S. Bae· 2 shared

Activity by Year

2020-2021 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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4 shared papersMicrobiology

C. Huttenhower

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Author profile →

4 papers

Recent·Most cited

MicrobiologybioRxivJan 20, 2021

{-}Multivariable Association Discovery in Population-scale Meta-omics Studies

H. Mallick, A. Rahnavard, L. J. McIver…·C. Huttenhower

This paper introduces MaAsLin 2, a method for analyzing multivariable associations in microbial multi-omics data, and applies it to reveal new insights into inflammatory bowel disease.

DOI 10.1371/journal.pcbi.1009442

humanmetagenomics

𝕏 PostBluesky

ImmunologybioRxivPreprintJan 8, 2021

Human gut bacteria produce TH17-modulating bile acid metabolites

D. Paik, L. Yao, Y. Zhang…·A. S. Devlin

This study identifies human gut bacteria that produce TH17-modulating bile acid metabolites, showing reduced levels in IBD patients.

DOI 10.1101/2021.01.08.425913

humanmetagenomics

𝕏 PostBluesky

ImmunologybioRxivJan 8, 2021

A Bacterial Bile Acid Metabolite Modulates Treg Activity through the Nuclear Hormone Receptor NR4A1

W. Li, S. Hang, Y. Fang…·J. R. Huh

This study identifies a bacterial bile acid metabolite, isoalloLCA, that enhances Treg cell differentiation via NR4A1 and is reduced in inflammatory bowel disease patients.

DOI 10.1016/j.chom.2021.07.013

humanmouse

𝕏 PostBluesky

MicrobiologybioRxivNov 19, 2020

Integrating taxonomic, functional, and strain-level profiling of diverse microbial communities with bioBakery 3

F. Beghini, L. J. McIver, A. Blanco-Miguez…·N. Segata

The paper introduces bioBakery 3, a set of tools for microbial community analysis, improving taxonomic, functional, and strain-level profiling with applications to CRC and IBD datasets.

DOI 10.7554/elife.65088

metagenomicsdeep learning

𝕏 PostBluesky