Author

E. A. Ostrander

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Evolutionary Biology· 3 Cancer Biology· 1

Signature Assays, Organisms & Methods

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Approach:statistical model· 4 Research Focus:chromatin & epigenetic regulation· 3 Assay:DNA methylation· 2 Assay:whole-genome sequencing· 2 Organism:bacteria (other)· 1 Organism:human· 1 Organism:mouse· 1 Organism:multiple species· 1

Frequent Co-Authors

A. N. Hogan· 2 shared A. Carmagnini· 1 shared A. Haghani· 1 shared A. Harris· 1 shared A. Naderi· 1 shared A. Seluanov· 1 shared A. T. Lu· 1 shared A.-R. Carvunis· 1 shared

Activity by Year

2019-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 17 mutual co-author links

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2 shared papersEvolutionary Biology

A. N. Hogan

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Author profile →

4 papers

Recent·Most cited

Imputation of ancient canid genomes reveals inbreeding history over the past 10,000 years

K. Bougiouri, S. G. Aninta, S. Charlton, A. Harris, A. Carmagnini, G. Piliciauskiene, T. R. Feuerborn, L. Scarsbrook, K. Tabadda, P. Blazevicius, H. G. Parker, S. Gopalakrishnan, G. Larson, E. A. Ostrander, E. K. Irving-Pease, , F. Racimo

This study imputes ancient dog and wolf genomes to analyze inbreeding history over 10,000 years, finding lower inbreeding in ancient populations and associations between low ROH regions and olfaction/immune genes.

bioRxiv · Mar 15, 2024Evolutionary Biology

Centuries of genome instability and evolution in soft-shell clam transmissible cancer

S. F. Hart, M. A. Yonemitsu, R. M. Giersch, B. F. Beal, G. Arriagada, B. W. Davis, E. A. Ostrander, S. P. Goff, M. J. Metzger

The paper analyzes the genome of a transmissible cancer in soft-shell clams to show its long evolutionary history and structural genomic instability over ~500 years.

bioRxiv · Aug 7, 2022Cancer Biology

DNA Methylation Networks Underlying Mammalian Traits

A. Haghani, A. T. Lu, C. Z. Li, T. R. Robeck, K. Belov, C. E. Breeze, R. T. Brooke, S. Clarke, C. G. Faulkes, Z. Fei, S. H. Ferguson, C. J. Finno, V. N. Gladyshev, V. Gorbunova, R. G. Goya, , S. Horvath

This study analyzes DNA methylation across 11,117 samples from 176 species to identify modules related to traits like age, lifespan, and phylogeny, revealing epigenetic patterns across evolution and aging.

bioRxiv · Mar 16, 2021Evolutionary Biology

Quantitative translation of dog-to-human aging by conserved remodeling of epigenetic networks

T. Wang, J. Ma, A. N. Hogan, S. Fong, K. Licon, B. Tsui, J. F. Kreisberg, P. D. Adams, A.-R. Carvunis, D. Bannasch, E. A. Ostrander, T. Ideker

This study translates dog-to-human aging by identifying conserved epigenetic changes, showing methylation patterns align physiological milestones across species.

bioRxiv · Nov 19, 2019 · PreprintEvolutionary Biology