Author

S. Charlton

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 2 Cell Biology· 1 Pathology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 3 Approach:experimental assay· 3 Research Focus:host-pathogen & immune response· 3 Research Focus:differential expression· 2 Organism:non-human primate· 2 Assay:proteomics· 2 Research Focus:spatial domain detection· 2 Research Focus:benchmarking· 1

Frequent Co-Authors

K. A. Ryan· 3 shared K. R. Bewley· 3 shared Y. Hall· 3 shared B. Hallis· 2 shared E. Brunt· 2 shared E. Rayner· 2 shared H. E. Humphries· 2 shared L. Allen· 2 shared

Activity by Year

2020-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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3 shared papersCell Biology

K. A. Ryan

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Evaluation of the cross reactivity of neutralising antibody response in vaccinated human and convalescent hamster sera against SARS-CoV-2 variants up to and including JN.1 using an authentic virus neutralisation assay

N. S. Coombes, K. R. Bewley, Y. Le Duff, N. Alami-Rahmouni, K. A. Ryan, S. Kempster, D. Ferguson, E. R. Davies, T. M. Weldon, E. S. Cross, L. Smith, C. Norris, K. R. Rogers-Broadway, K. Lewandowski, S. Treagus, , S. G. P. Funnell

This study evaluates neutralising antibody responses in vaccinated humans and convalescent hamsters against SARS-CoV-2 variants up to JN.1 using an authentic virus neutralisation assay, finding increased resistance to JN.1 in vaccinated individuals and specific neutralisation patterns in hamsters.

bioRxiv · Oct 21, 2023 · PreprintCell Biology

Polysaccharide breakdown products drive degradation-dispersal cycles of foraging bacteria through changes in metabolism and motility

A. K. M. Stubbusch, J. M. Keegstra, J. Schwartzman, S. Pontrelli, E. E. Clerc, S. Charlton, R. Stocker, C. Magnabosco, O. T. Schubert, M. Ackermann, G. G. D'Souza

This study shows that marine bacteria switch from polysaccharide degradation to motility when exposed to breakdown products, enabling dispersal to new nutrient sources.

bioRxiv · Jul 14, 2023Microbiology

Dose-dependent response to infection with SARS-CoV-2 in the ferret model: evidence of protection to re-challenge

K. A. Ryan, K. R. Bewley, S. A. Fotheringham, P. Brown, Y. Hall, A. C. Marriott, J. A. Tree, L. Allen, M. J. Aram, E. Brunt, K. R. Buttigieg, B. E. Cavell, D. P. Carter, R. Cobb, N. S. Coombes, , M Dennis

This study investigates the dose-dependent response of ferrets to SARS-CoV-2 infection, showing protection against re-challenge and mild clinical disease.

Nature Communications · Jan 4, 2021Peer-reviewedMicrobiology

Immunological and pathological outcomes of SARS-CoV-2 challenge after formalin-inactivated vaccine immunisation of ferrets and rhesus macaques

K. R. Bewley, K. E. R. Gooch, K. M. Thomas, S. R. Longet, N. Wiblin, L. Hunter, K. Chan, P. Brown, R. A. Russell, C. Ho, G. Slack, H. E. Humphries, L. Alden, L. Allen, M. Aram, , M. Carroll

This study evaluates vaccine-enhanced disease in ferrets and rhesus macaques after formalin-inactivated SARS-CoV-2 vaccination, finding mild transient lung pathology but no significant enhancement.

bioRxiv · Dec 21, 2020Pathology