E. Fischer

Flumequine, a fluoroquinolone in disguise

The paper investigates whether flumequine selects for the same resistance mechanisms in E. coli as enrofloxacin, finding similar SNPs in gyrA and comparable resistance rates.

A tunable and versatile chemogenetic near infrared fluorescent reporter

The paper introduces nirFAST, a tunable NIR fluorescent reporter for multiplexed imaging, enabling subdiffraction resolution and cell cycle monitoring in live cells.

Cigarette smoking promotes the spread of antimicrobial resistance in the human lung and the environment

This study shows cigarette smoke increases antimicrobial resistance transfer between bacteria in lung and environmental settings.

Anopheles salivary apyrase regulates blood meal hemostasis and drives malaria parasite transmission

This study shows that Anopheles salivary apyrase promotes Plasmodium transmission by modulating hemostasis during blood feeding.

A Bayesian inference method to estimate transmission trees with multiple introductions; applied to SARS-CoV-2 in Dutch mink farms.

Multi-omic profiling of breast cancer cells uncovers stress MAPK-associated sensitivity to AKT degradation

This study develops a second-generation AKT degrader, INY-05-040, showing improved efficacy over existing inhibitors in breast cancer cells by inducing stress MAPK signaling.

Respiratory disease and virus shedding in rhesus macaques inoculated with SARS-CoV-2

This study shows that SARS-CoV-2 causes respiratory disease in rhesus macaques with symptoms similar to human cases, including prolonged viral shedding.

Losing maternal care: Neotenic gene expression in the preoptic area of avian brood parasites

The paper compares gene expression in the preoptic area of brood parasitic and non-parasitic birds to investigate molecular mechanisms of maternal behavior loss, finding evidence for neotenic gene expression.