Author

T. L. Alves e Silva

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 3 Immunology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Research Focus:host-pathogen & immune response· 3 Organism:plant (other)· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Organism:Drosophila· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

J. Vega-Rodriguez· 4 shared A. Dziedziech· 1 shared A. Jex· 1 shared B. Balan· 1 shared B. Brown· 1 shared B. Crews· 1 shared B. Jenkins· 1 shared C. Carmona-Rivera· 1 shared

Activity by Year

2020-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 18 mutual co-author links

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4 shared papersMicrobiology

J. Vega-Rodriguez

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4 papers

Recent·Most cited

MicrobiologybioRxivPreprintMay 22, 2023

Anopheles salivary apyrase regulates blood meal hemostasis and drives malaria parasite transmission

Z. R. Pala, T. L. Alves e Silva, M. Minai…·J. Vega-Rodriguez

This study shows that Anopheles salivary apyrase promotes Plasmodium transmission by modulating hemostasis during blood feeding.

DOI 10.1101/2023.05.22.541827

experimental assayhost-pathogen & immune response

𝕏 PostBluesky

MicrobiologybioRxivApr 5, 2022

Single-cell transcriptomics to define Plasmodium falciparum stage-transition in the mosquito midgut

M. Mohammed, A. Dziedziech, V. Sekar…·J. Ankarklev

This study uses single-cell transcriptomics to analyze Plasmodium falciparum development in the mosquito midgut, identifying transcriptional trajectories and stress responses, including genes encoding intrinsically disordered proteins.

DOI 10.1128/spectrum.03671-22

plant (other)bulk RNA-seq

𝕏 PostBluesky

ImmunologybioRxivPreprintSep 25, 2020

A high affinity human monoclonal antibody against Pfs230 binds multiple parasite stages and blocks oocyst formation in mosquitoes

C. H. Coelho, W. K. Tang, M. Burkhardt…·P. Duffy

The paper identifies a high-affinity human monoclonal antibody against Pfs230 that blocks oocyst formation in mosquitoes by targeting gamete surfaces.

DOI 10.1101/2020.09.25.313478

humanplant (other)

𝕏 PostBluesky

MicrobiologybioRxivJun 19, 2020

The 20-hydroxyecdysone agonist, halofenozide, promotes anti-Plasmodium immunity in Anopheles gambiae via the ecdysone receptor

R. A. Reynolds, H. Kwon, T. L. Alves e Silva…·R. C. Smith

This study shows that halofenozide, a 20-hydroxyecdysone agonist, reduces Plasmodium infection in Anopheles gambiae by activating the ecdysone receptor via ultraspiracle, without affecting cellular immunity or AMP production.

DOI 10.1038/s41598-020-78280-8

Drosophilaexperimental assay

𝕏 PostBluesky