Author

B. Williamson

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 8 Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 9 Research Focus:host-pathogen & immune response· 8 Organism:rat· 5 Organism:mouse· 3 Research Focus:cell type annotation· 2 Research Focus:cell-cell communication· 2 Research Focus:differential expression· 2 Research Focus:drug response / drug discovery· 2

Frequent Co-Authors

E. de Wit· 8 shared N. van Doremalen· 7 shared V. Munster· 7 shared A. Okumura· 6 shared F. Feldmann· 6 shared G. Saturday· 6 shared P. Hanley· 6 shared J. Lovaglio· 5 shared

Activity by Year

2020-2024 · peak 4/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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Curved chords = mutual co-authorship

8 shared papersMicrobiology

E. de Wit

Mutual co-authors in cluster

Author profile →

9 papers

Recent·Most cited

Evolution of Omicron lineage towards increased fitness in the upper respiratory tract in the absence of severe lung pathology

A. Wickenhagen, M. Flagg, J. Port, C. K. Yinda, K. Goldin, S. Gallogly, J. E. Schulz, T. Lutterman, B. Williamson, F. Kaiser, R. Mukesh, S. Van Tol, B. Smith, N. van Doremalen, C. Russell, , V. Munster

This study evaluates the fitness and pathogenesis of Omicron variants in the upper and lower respiratory tracts, finding increased URT fitness with reduced lung pathology.

bioRxiv · Jun 13, 2024Microbiology

SARS-CoV-2 Omicron BA.1 and BA.2 are attenuated in rhesus macaques as compared to Delta

N. van Doremalen, M. Singh, T. Saturday, K. C. Yinda, L. Perez-Perez, W. F. Bohler, Z. Weishampel, M. Lewis, J. Schulz, B. Williamson, K. Meade-White, S. Gallogly, A. Okumura, F. Feldmann, J. Lovaglio, , K. Rosenke

This study compares disease severity and viral load in rhesus macaques infected with SARS-CoV-2 Delta, Omicron BA.1, and BA.2 variants, finding Omicron variants cause less severe disease with lower viral loads.

bioRxiv · Aug 1, 2022Microbiology

Impact of Erg11 amino acid substitutions identified in Candida auris clade III isolates on triazole drug susceptibility

B. Williamson, A. Wilk, K. D. Guerrero, T. D. Mikulski, T. N. Elias, I. Sawh, G. Cancino-Prado, D. Gardam, C. H. Heath, N. P. Govender, D. S. Perlin, M. Kordalewska, K. R. Healey

bioRxiv · Aug 16, 2021Microbiology

Subtle differences in the pathogenicity of SARS-CoV-2 variants of concern B.1.1.7 and B.1.351 in rhesus macaques

V. Munster, M. Flagg, M. Singh, B. Williamson, F. Feldmann, L. Perez-Perez, B. Brumbaugh, M. Holbrook, D. Adney, A. Okumura, P. Hanley, B. Smith, J. Lovaglio, S. Anzick, C. Martens, , E. de Wit

This study compares the pathogenicity of SARS-CoV-2 variants B.1.1.7 and B.1.351 in rhesus macaques, finding differences in clinical outcomes and immune responses.

bioRxiv · May 7, 2021Microbiology

ChAdOx1 nCoV-19 (AZD1222) protects Syrian hamsters against SARS-CoV-2 B.1.351 and B.1.1.7 1 disease

R. Fischer, N. van Doremalen, D. Adney, C. Yinda, J. Port, M. Holbrook, J. Schulz, B. Williamson, T. Thomas, K. Barbian, S. Anzick, S. Ricklefs, B. Smith, D. Long, C. Martens, , V. Munster

This study shows that the ChAdOx1 nCoV-19 vaccine protects Syrian hamsters from SARS-CoV-2 B.1.1.7 and B.1.351 variants, preventing weight loss, lung lesions, and viral replication.

bioRxiv · Mar 11, 2021Microbiology

Hydroxychloroquine Proves Ineffective in Hamsters and Macaques Infected with SARS-CoV-2

K. Rosenke, M. Jarvis, F. Feldmann, B. Schwarz, A. Okumura, J. Lovaglio, G. Saturday, P. Hanley, K. Meade-White, B. Williamson, F. Hansen, L. Perez-Perez, S. Leventhal, T.-L. Tang-Huau, M. Nason, , H. Feldmann

This study shows hydroxychloroquine does not reduce SARS-CoV-2 replication or improve clinical outcomes in hamsters or macaques.

bioRxiv · Jun 10, 2020 · PreprintPharmacology & Toxicology

ChAdOx1 nCoV-19 vaccination prevents SARS-CoV-2 pneumonia in rhesus macaques

N. van Doremalen, T. Lambe, A. Spencer, S. Belij-Rammerstorfer, J. Purushotham, J. Port, V. Avanzato, T. Bushmaker, A. Flaxman, M. Ulaszewska, F. Feldmann, E. Allen, H. Sharpe, J. Schulz, M. Holbrook, , V. Munster

This study shows that the ChAdOx1 nCoV-19 vaccine reduces SARS-CoV-2 viral load and prevents pneumonia in rhesus macaques without causing immune-enhanced disease.

bioRxiv · May 13, 2020 · PreprintMicrobiology

Clinical benefit of remdesivir in rhesus macaques infected with SARS-CoV-2

B. Williamson, F. Feldmann, B. Schwarz, K. Meade-White, D. Porter, J. Schulz, N. van Doremalen, I. Leighton, C. K. Yinda, L. Perez-Perez, A. Okumura, J. Lovaglio, P. Hanley, G. Saturday, C. Bosio, , E. de Wit

This study shows remdesivir reduces SARS-CoV-2 viral load and lung damage in rhesus macaques when administered early in infection.

bioRxiv · Apr 15, 2020Microbiology

Respiratory disease and virus shedding in rhesus macaques inoculated with SARS-CoV-2

V. Munster, F. Feldmann, B. Williamson, N. van Doremalen, , L. Perez-Perez, J. Schultz, K. Meade-White, A. Okumura, J. Callison, B. Brumbaugh, V. Avanzato, R. Rosenke, P. Hanley, G. Saturday, D. Scott, , E. de Wit

This study shows that SARS-CoV-2 causes respiratory disease in rhesus macaques with symptoms similar to human cases, including prolonged viral shedding.

bioRxiv · Mar 21, 2020Microbiology