Author

N. Crosetto

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 2 Cancer Biology· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Organism:human· 4 Approach:experimental assay· 3 Research Focus:cancer & tumor microenvironment· 2 Research Focus:cell type annotation· 2 Research Focus:chromatin & epigenetic regulation· 2 Assay:DNA methylation· 2 Approach:statistical model· 2 Assay:whole-genome sequencing· 2

Frequent Co-Authors

A. Papantonis· 2 shared E. G. Gusmao· 2 shared V. Roukos· 2 shared A. Angelopoulou· 1 shared A. Iftekhar· 1 shared A. Maya-Mendoza· 1 shared A. Mizi· 1 shared A. Polyzos· 1 shared

Activity by Year

2018-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 17 mutual co-author links

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2 shared papersCell Biology

A. Papantonis

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

High clonal diversity and spatial genetic admixture in early prostate cancer and surrounding normal tissue

N. Zhang, L. Harbers, M. Simonetti, C. Diekmann, Q. Verron, E. Berrino, S. E. Bellomo, G. M. C. Longo, M. Ratz, N. Schultz, F. Tarish, P. Su, B. Han, W. Wang, S. Onorato, , N. Crosetto

bioRxiv · Nov 7, 2023Cancer Biology

Genomic instability is an early event driving chromatin reorganization and escape from oncogene-induced senescence

C. Zampetidis, P. Galanos, A. Angelopoulou, Y. Zhu, T. Karamitros, N. Lagopati, R. Mirzazadeh, A. Polyzos, S. Garnerone, E. G. Gusmao, K. Sofiadis, D. E. Pefani, M. Demaria, N. Crosetto, A. Maya-Mendoza, , V. G. Gorgoulis

The paper identifies an early chromosomal inversion that enables escape from oncogene-induced senescence by activating BHLHE40 and promoting malignant transformation.

bioRxiv · Dec 20, 2020Cell Biology

Colibactin DNA damage signature indicates causative role in colorectal cancer

P. J. Dziubanska Kusibab, H. Berger, F. Battistini, B. A. Bowman, A. Iftekhar, R. Katainen, N. Crosetto, M. Orozco, L. A. Aaltonen, T. F. Meyer

The paper identifies a mutational signature caused by colibactin in human colorectal cancers.

bioRxiv · Oct 25, 2019 · PreprintMicrobiology

Spatial chromosome folding and active transcription drive DNA fragility and formation of oncogenic MLL translocations

H. J. Gothe, B. A. M. Bouwman, E. G. Gusmao, R. Piccinno, S. Sayols, O. Drechsel, G. Petrosino, V. Minneker, N. Josipovic, A. Mizi, C. F. Nielsen, E.-M. Wagner, S. Takeda, H. Sasanuma, D. F. Hudson, , V. Roukos

The paper shows that transcription and spatial chromosome folding increase DNA fragility, leading to oncogenic translocations in leukemia.

bioRxiv · Dec 3, 2018Cell Biology