ImmunologybioRxivPreprint
Immune responses in pancreatic cancer may be restricted byprevalence of activated regulatory T-cells, dysfunctionalCD8+ T-cells, and senescent T-cells
S. Sivakumar, E. Abu-Shah, D. Ahern…·M. Dustin
This study identifies immune cell states in pancreatic cancer, showing regulatory T-cells and dysfunctional CD8+ T-cells contribute to a suppressive microenvironment, suggesting new therapeutic targets.
DOI 10.1101/2020.06.20.163071