Cancer BiologybioRxivPreprint
SIX4 Controls STING Expression Enhancing anti-PD-1 Efficacy
B. Liang, E. H. Zhang, Z. Ye…·J. J. Wang
This study identifies SIX4 as a regulator of STING expression in colon cancer, showing it enhances anti-PD-1 therapy efficacy by promoting STING activation and CD8+ T-cell infiltration.