Author

S. Juul

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 3 Evolutionary Biology· 2 Cancer Biology· 1 Cell Biology· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 5 Approach:experimental assay· 5 Research Focus:chromatin & epigenetic regulation· 3 Research Focus:development & morphogenesis· 3 Organism:human· 3 Assay:long-read sequencing· 3 Approach:statistical model· 3 Approach:deep learning· 2

Frequent Co-Authors

X. Dai· 6 shared S. Hickey· 5 shared E. Harrington· 4 shared D. J. Turner· 3 shared J. Beaulaurier· 3 shared P. Rughani· 3 shared A. W. Drong· 2 shared C. Tyer· 2 shared

Activity by Year

2019-2024 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 34 mutual co-author links

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6 shared papersMicrobiology

X. Dai

Mutual co-authors in cluster

Author profile →

8 papers

Recent·Most cited

De novo antibody discovery in human blood from full-length single B cell transcriptomics and matching haplotyped-resolved germline assemblies

J. Beaulaurier, L. Ly, J. A. Duty, C. Tyer, C. Stevens, C.-t. Hung, A. Sookdeo, A. W. Drong, S. Kowdle, D. J. Turner, S. Juul, S. Hickey, B. Lee

This study uses single-cell transcriptomics and germline haplotype assembly to discover antibodies from human blood post-MMR vaccination, showing neutralization of measles virus.

bioRxiv · Mar 26, 2024 · PreprintImmunology

High resolution long-read telomere sequencing reveals dynamic mechanisms in aging and cancer

T. T. Schmidt, C. Tyer, P. Rughani, C. Haggblom, J. R. Jones, X. Dai, K. A. Frazer, F. H. Gage, S. Juul, S. Hickey, J. Karlseder

This study introduces Telo-seq, a method using long-read sequencing to measure telomere lengths with high resolution, revealing dynamics in aging and cancer.

bioRxiv · Nov 28, 2023Cell Biology

Borg extrachromosomal elements of methane-oxidizing archaea have conserved and expressed genetic repertoires

M. C. Schoelmerich, L. Ly, J. West-Roberts, L.-D. Shi, C. Shen, N. Malvankar, N. Taib, S. Gribaldo, B. J. Woodcroft, B. Al-Shayeb, X. Dai, C. Mozsary, S. Hickey, C. He, J. A. Beaulaurier, , J. Banfield

The paper identifies conserved genetic repertoires in Borg extrachromosomal elements of methane-oxidizing archaea and shows their higher expression than host genes.

bioRxiv · Aug 1, 2023Microbiology

Single-cell multi-omics defines the cell-type specific impact of splicing aberrations in human hematopoietic clonal outgrowths

F. Gaiti, P. Chamely, A. G. Hawkins, M. Cortes-Lopez, A. D. Swett, S. Ganesan, T. H. Mouhieddine, X. Dai, L. Kluegel, C. Chen, K. Batta, J. Beaulaurier, A. W. Drong, S. Hickey, N. Dusaj, , D. A. Landau

This study introduces GoT-Splice, a multi-omics method to analyze splicing aberrations in human hematopoietic cells, revealing cell-type specific effects of SF3B1 mutations in clonal outgrowths.

bioRxiv · Jun 8, 2022 · PreprintCancer Biology

Selection on ancient variations drives the adaptive radiation of Metrosideros across the Hawaiian archipelago

J. Y. Choi, X. Dai, J. Z. Peng, P. Rughani, S. Hickey, E. Harrington, S. Juul, J. Ayroles, M. Purugganan, E. Stacy

This study investigates how ancient genetic variations drive adaptive radiation in Hawaiian Metrosideros, showing balancing selection on pre-existing haplotypes facilitates diversification despite limited genetic diversity.

bioRxiv · Nov 3, 2020 · PreprintEvolutionary Biology

Commensalism in the Mimiviridae giant virus family

S. Jeudy, L. Bertaux, J.-M. Alempic, A. Lartigue, M. Legendre, L. Belmudes, S. Santini, N. Philippe, L. Beucher, E. G. Biondi, S. Juul, D. J. Turner, Y. Coute, J.-M. Claverie, C. Abergel

This study investigates the interaction network between a virophage, transpovirons, and their host giant viruses, revealing a form of commensalism where transpovirons use virophages to propagate without affecting the host virus's infectious cycle.

bioRxiv · Sep 25, 2019 · PreprintMicrobiology

Nanopore-based genome assembly and the evolutionary genomics of basmati rice

J. Y. Choi, Z. Lye, S. Groen, X. Dai, P. Rughani, S. Zaaijer, E. Harrington, S. Juul, M. Purugganan

The paper assembles high-quality genomes of two basmati rice varieties using nanopore sequencing and identifies structural variations, gene flow, and genetic groupings in circum-basmati rice.

bioRxiv · Aug 13, 2019 · PreprintEvolutionary Biology

Assembly-free single-molecule nanopore sequencing recovers complete virus genomes from natural microbial communities

J. Beaulaurier, E. Luo, J. Eppley, P. Den Uyl, X. Dai, D. J. Turner, M. Pendleton, S. Juul, E. Harrington, E. F. DeLong

This study develops an assembly-free nanopore sequencing method to recover complete virus genomes from environmental samples, revealing new viral structures and genomic features.

bioRxiv · Apr 26, 2019Microbiology