Author

E. Jaimon

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 2 Cell Biology· 2

Signature Assays, Organisms & Methods

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Organism:mouse· 4 Research Focus:cell signaling & trafficking· 3 Research Focus:cell type annotation· 3 Approach:experimental assay· 3 Assay:proteomics· 3 Research Focus:development & morphogenesis· 1 Research Focus:differential expression· 1 Approach:genetic perturbation / CRISPR· 1

Frequent Co-Authors

F. Tonelli· 3 shared S. R. Pfeffer· 3 shared D. R. Alessi· 2 shared Y.-E. Lin· 2 shared A. Jose· 1 shared A. Priya· 1 shared C. Limouse· 1 shared C. Themistokleous· 1 shared

Activity by Year

2022-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 23 mutual co-author links

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3 shared papersBiochemistry

F. Tonelli

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Pathogenic LRRK2 mutations cause loss of primary cilia and Neurturin in striatal Parvalbumin interneurons

Y.-E. Lin, E. Jaimon, F. Tonelli, S. R. Pfeffer

The paper shows that LRRK2 mutations cause loss of primary cilia and Neurturin in striatal Parvalbumin interneurons, impairing neuroprotective signaling.

bioRxiv · Jun 17, 2024Cell Biology

Endogenous LRRK2 and PINK1 function in a convergent neuroprotective ciliogenesis pathway in the brain

E. Bagnoli, Y.-E. Lin, S. Burel, E. Jaimon, O. Antico, C. Themistokleous, J. Nikoloff, I. Morella, J. Watzlawik, F. Fiesel, W. Springer, F. Tonelli, S. Brooks, S. Dunnett, R. Brambilla, , M. Muqit

This study shows LRRK2 and PINK1 function in parallel neuroprotective pathways affecting ciliogenesis in Parkinson's disease, suggesting shared therapeutic targets.

bioRxiv · Jun 11, 2024Biochemistry

Genome-wide screen reveals Rab12 GTPase as a critical activator of pathogenic LRRK2 kinase

H. S. Dhekne, F. Tonelli, W. M. Yeshaw, C. Y. Chiang, C. Limouse, E. Jaimon, E. Purlyte, D. R. Alessi, S. R. Pfeffer

The paper identifies Rab12 as a critical activator of pathogenic LRRK2 kinase through a CRISPR-based screen and structural analysis.

bioRxiv · Feb 17, 2023Biochemistry

Insights into cargo sorting by SNX32 in neuronal and non-neuronal cells: physiological implications in neurite outgrowth

S. Datta, J. Sugatha, A. Priya, P. Raj, E. Jaimon, A. Jose

This study identifies SNX32's role in cargo sorting via its PX and BAR domains, showing its involvement in transferrin trafficking and neuronal differentiation.

bioRxiv · Nov 4, 2022Cell Biology