Lin28b specifies an innate-like lineage of CD8+ T cells in early life
N. Watson, R. Patel, O. Oyesola, N. Laniewski, J. Grenier, J. Wang, C. Tabilas, K. J. Y. Mon, S. Peng, S. Wesnak, K. Nzingha, N. Smith, M. Davenport, E. T. Wojno, K. Scheible, , B. Rudd
The paper shows Lin28b programs neonatal CD8+ T cells to have innate defense capabilities through transcriptional and epigenetic changes.
bioRxiv · Feb 14, 2022 · PreprintImmunology