Cell BiologyJournal of the American Society of NephrologyPeer-reviewed
WWP2 MEDIATES THE METABOLIC REPROGRAMMING OF RENAL MYOFIBROBLASTS TO PROMOTE KIDNEY FIBROSIS
H. Chen, R. You, J. Guo…·E. G. Petretto
This paper identifies WWP2 as a regulator of myofibroblast metabolic reprogramming in renal fibrosis, showing it suppresses PGC-1 to alter metabolic pathways and reduce fibrosis severity.