Author

E. Lou

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 5 Bioengineering· 1 Cell Biology· 1 Pathology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Organism:human· 4 Approach:statistical model· 3 Research Focus:drug response / drug discovery· 2 Research Focus:gene regulatory network inference· 2 Research Focus:host-pathogen & immune response· 2 Organism:mouse· 2 Research Focus:benchmarking· 1

Frequent Co-Authors

M. Bazzaro· 3 shared M. Shetty· 2 shared V. Clemente· 2 shared A. C. Nelson· 1 shared A. Hoshino· 1 shared A. K. Li· 1 shared A. Mooneyham· 1 shared A. Nelson· 1 shared

Activity by Year

2018-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 17 mutual co-author links

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3 shared papersPathology

M. Bazzaro

Mutual co-authors in cluster

Author profile →

8 papers

Recent·Most cited

Early ctDNA kinetics as a dynamic biomarker of cancer treatment response

A. K. Li, E. Lou, K. Leder, J. Foo

This study develops a framework to design ctDNA biomarkers for cancer treatment response by modeling ctDNA kinetics and simulating virtual patient cohorts.

bioRxiv · Jul 1, 2024Cancer Biology

Clinical Significance of the Stromatic Component in Ovarian Cancer: Quantity Over Quality in Outcome Prediction

E. Lou, V. Clemente, M. Grube, A. Svedbom, A. C. Nelson, F. Blome, A. Staebler, S. Kommoss, M. Bazzaro

This study shows that higher tumor-stroma proportion (TSP) in ovarian cancer is linked to worse patient outcomes, including shorter progression-free and overall survival, and increased chemoresistance.

bioRxiv · Jun 27, 2023 · PreprintPathology

Treatment with Tumor-Treating Fields (TTFields) Suppresses Intercellular Tunneling Nanotube Formation In Vitro and Upregulates Immuno-Oncologic Biomarkers In Vivo in Malignant Mesothelioma

A. Sarkari, S. Korenfeld, K. Ladner, P. Wong, S. Padmanabhan, R. I. Vogel, L. Sherer, N. Courtemanche, C. Steer, K. Wainer-Satsir, E. Lou

bioRxiv · Dec 29, 2022Cancer Biology

GLS1 is a Protective Factor Rather than a Molecular Target in ARID1A-Mutated Ovarian Clear Cell Carcinoma

V. Clemente, A. Nelson, B. Erickson, R. Baker, N. Rubin, M. Khalifa, A. Hoshino, M. Shetty, E. Lou, M. Bazzaro

The paper investigates GLS1 expression in ARID1A-mutated ovarian clear cell carcinoma and finds it is not correlated with ARID1A loss and is associated with better clinical outcomes.

bioRxiv · Sep 3, 2021 · PreprintCancer Biology

Genetic editing of CISH enhances T cell effector programs independently of immune checkpoint cell surface ligand expression

E. Arthofer, K. Chakraborty, L. Viney, M. J. Johnson, B. R. Webber, B. S. Moriarity, E. Lou, M. Choudhry, C. A. Klebanoff, T. Henley

This study shows that genetic editing of CISH enhances T cell anti-tumor activity independently of PD-L1 expression, outperforming PD-1 and TIGIT disruption in certain contexts.

bioRxiv · Aug 17, 2021 · PreprintCancer Biology

Chemotherapy but not the tumor-draining lymph nodes determine the immunotherapy response in secondary tumors

X. Zhao, B. Kassaye, D. Wangmo, E. Lou, S. Subramanian

This study shows that chemotherapy, not tumor-draining lymph nodes, determines immunotherapy response in secondary tumors using mouse models.

bioRxiv · Apr 8, 2020Cancer Biology

UNC-45A is preferentially expressed in epithelial cells and binds to and co-localizes with interphase MTs

J. Habicht, A. Mooneyham, M. Shetty, X. Zhang, V. Shridhar, B. Winterhoff, Y. Zhang, J. Cepela, T. Starr, E. Lou, M. Bazzaro

This paper shows UNC-45A is preferentially expressed in epithelial cells and co-localizes with microtubules in interphase cells, independent of actin or myosin.

Cancer Biology & Therapy · Jul 22, 2019Peer-reviewedCell Biology

Real time monitoring of transtibial elevated vacuum prostheses: a case series on socket air pressure

K. R. Schoepp, J. S. Schofield, D. Home, M. R. Dawson, E. Lou, M. Keri, P. D. Marasco, J. S. Hebert

This study monitors socket air pressure in transtibial prostheses during functional tasks, showing variability in vacuum levels and gait profiles among users.

bioRxiv · Aug 9, 2018Bioengineering