Gluebodies improve crystal reliability and diversity through transferable nanobody mutations that introduce constitutive close contacts
M. Ye, M. Makola, J. Newman, M. Fairhead, E. MacLean, N. D. Wright, L. Koekemoer, A. Thompson, G. A. Bezerra, G. Yi, H. Li, V. L. Rangel, D. Mamalis, H. Aitkenhead, B. G. Davis, , F. von Delft
The paper engineers nanobody interfaces to improve crystal reliability and diversity, resulting in better diffraction and multiple polymorphs.
bioRxiv · Jul 26, 2022 · PreprintBiochemistry