Author

E. Malekos

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 4

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 3 Research Focus:cell type annotation· 2 Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Organism:human· 2 Organism:mouse· 2 Research Focus:cell signaling & trafficking· 1 Approach:deep learning· 1

Frequent Co-Authors

S. CarpenteriD· 4 shared S. Katzman· 3 shared C. Montano· 2 shared L. Sudek· 2 shared S. Covarrubias· 2 shared A. Capili· 1 shared A. Coleman· 1 shared C. G. Weindel· 1 shared

Activity by Year

2023-2024 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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4 shared papersImmunology

S. CarpenterORCID

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Author profile →

4 papers

Recent·Most cited

Identification and Functional Characterization of lncRNAs involved in Human Monocyte-to-Macrophage Differentiation

S. Carpenter, C. Montano, S. Covarrubias, E. Malekos, S. Katzman

The paper identifies and functionally characterizes lncRNAs involved in human monocyte-to-macrophage differentiation using RNA-seq and high-throughput screening.

RNA Biology · Oct 21, 2024Peer-reviewedImmunology

CRISPRi screens identify the lncRNA, LOUP, as a multifunctional locus regulating macrophage differentiation epigenetically and inflammatory signaling through a short, encoded peptide

H. Halasz, E. Malekos, S. Covarrubias, S. Yitiz, C. Montano, L. Sudek, S. Katzman, S. J. Liu, M. A. Horlbeck, J. S. Weissman, S. Carpenter

The paper uses CRISPRi screens to identify the lncRNA LOUP as a regulator of macrophage differentiation and inflammatory signaling through epigenetic and peptide-mediated mechanisms.

bioRxiv · Dec 19, 2023 · PreprintImmunology

The RNA binding protein, HNRNPA2B1, regulates IFNG signaling in macrophages

M. Mohammed Salih, C. G. Weindel, E. Malekos, L. Sudek, S. Katzman, C. J. Mabry, A. Coleman, S. Azam, R. O. Watson, K. L. Patrick, S. Carpenter

This study shows HNRNPA2B1 regulates IFNG signaling in macrophages by controlling IFNG receptor splicing and bacterial restriction.

bioRxiv · Oct 12, 2023 · PreprintImmunology

LincRNA-Cox2 regulates smoke-induced inflammation in murine macrophages

S. Carpenter, M. M. Salih, E. K. Robinson, E. Malekos, E. Perez, A. Capili, K. Kim, W. Z. Zhang, S. M. Clonnan

This study identifies lincRNA-Cox2 as a regulator of smoke-induced inflammation in murine macrophages, showing its role in modulating inflammatory gene expression and splicing.

American Journal of Respiratory Cell and Molecular Biology · May 1, 2023Peer-reviewedImmunology