Author

E. Perez

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 3 Immunology· 2 Physiology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 4 Approach:experimental assay· 4 Organism:mouse· 3 Research Focus:differential expression· 2 Organism:human· 2 Research Focus:protein folding & dynamics· 2 Assay:proteomics· 2 Approach:statistical model· 2

Frequent Co-Authors

A. Aris· 1 shared A. Capili· 1 shared A. Krueger· 1 shared A. M. Feldman· 1 shared A. Pitarch· 1 shared A. Sanchez-Chardi· 1 shared A. Vasudev· 1 shared A. Villaverde· 1 shared

Activity by Year

2018-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 6 mutual co-author links

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1 shared paperMicrobiology

A. Aris

Mutual co-authors in cluster

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6 papers

Recent·Most cited

LincRNA-Cox2 regulates smoke-induced inflammation in murine macrophages

S. Carpenter, M. M. Salih, E. K. Robinson, E. Malekos, E. Perez, A. Capili, K. Kim, W. Z. Zhang, S. M. Clonnan

This study identifies lincRNA-Cox2 as a regulator of smoke-induced inflammation in murine macrophages, showing its role in modulating inflammatory gene expression and splicing.

American Journal of Respiratory Cell and Molecular Biology · May 1, 2023Peer-reviewedImmunology

An early decline in ETPs reflects reduced pre-thymic progenitors and altered signals from the thymus microenvironment

J. Srinivasan, A. Vasudev, H. J. Selden, E. Perez, B. J. LaFleur, S. A. Sinari, A. Krueger, E. R. Richie, L. I. R. Ehrlich

The paper shows that early T-cell progenitors decline by 3 months in mice due to reduced pre-thymic progenitors and diminished Notch signaling.

bioRxiv · Jan 18, 2022 · PreprintImmunology

Distinct human gut microbial taxonomic signatures uncovered with different sample processing and microbial cell disruption methods for metaproteomic analysis

C. Garcia-Duran, R. Martinez-Lopez, I. Zapico, E. Perez, E. Romeu, J. Arroyo, M. L. Hernaez, A. Pitarch, L. Monteoliva Diaz, C. Gil

This study evaluates different sample processing and microbial cell disruption methods for metaproteomic analysis of the human gut microbiota, identifying method-specific taxonomic and functional signatures.

bioRxiv · Oct 8, 2020 · PreprintMicrobiology

Cardiomyocyte Contractile Impairment in Heart Failure Results from Reduced BAG3-mediated Sarcomeric Protein Turnover

T. G. Martin, V. D. Myers, P. Dubey, E. Perez, C. S. Morevac, M. S. Willis, A. M. Feldman, J. A. Kirk

The paper shows reduced BAG3-mediated sarcomere turnover causes cardiomyocyte contractile impairment in heart failure, with gene therapy restoring function in mice.

bioRxiv · Apr 10, 2020Physiology

Aggregation-prone peptides modulate interferon gamma functionality in naturally occurring protein nanoparticles

J. V. Carratala, O. Cano-Garrido, J. M. Sanchez, C. Membrado, E. Perez, O. Conchillo-Sole, X. Daura, A. Sanchez-Chardi, A. Villaverde, A. Aris, E. Garcia-Fruitos, N. Ferrer-Miralles

This study shows that aggregation-prone peptides enhance the formation of protein nanoparticles from interferon-gamma in Lactococcus lactis, with compact protein conformations correlating with increased biological activity.

bioRxiv · Jan 3, 2019 · PreprintMicrobiology

Pervasive within-host recombination and epistasis as major determinants of the molecular evolution of the Foot-and-Mouth Disease Virus capsid

L. Ferretti, E. Perez, F. Zhang, F. Maree, L.-M. de Klerk-Lorist, L. van Schalkwykc, N. D. Juleff, B. Charleston, P. Ribeca

This paper shows that within-host recombination and epistasis significantly drive molecular evolution of FMDV capsid genes, with recombination rates comparable to mutation rates.

bioRxiv · Dec 12, 2018Microbiology