ImmunologybioRxivPreprint
Exosome based multivalent vaccine: achieving potent immunization, broadened reactivity, and strong T cell responses with nanograms of proteins
M. Cacciottolo, J. B. Nice, Y. Li…·M. Sun
This paper develops a multivalent exosome-based vaccine using nanogram doses of SARS-CoV-2 proteins without adjuvant, showing strong immune responses and cross-reactivity against variants.