Author

J. B. Nice

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 3 Biophysics· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Organism:bacteria (other)· 2 Research Focus:cell type annotation· 2 Research Focus:host-pathogen & immune response· 2 Organism:mouse· 2 Assay:proteomics· 2 Research Focus:drug response / drug discovery· 1 Organism:human· 1

Frequent Co-Authors

C. L. Mora· 3 shared J. Angeles· 3 shared K. Elliott· 3 shared M. Cacciottolo· 3 shared m. sun· 3 shared M. Young· 3 shared R. Twaddle· 3 shared Y. Li· 3 shared

Activity by Year

2022-2023 · peak 4/yr

Co-Author Collaboration Network

10 top collaborators · 36 mutual co-author links

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3 shared papersImmunology

C. L. Mora

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

Multivalent Exosome based protein vaccine: a "mix and match" approach to epidemic viruses' challenges.

M. Cacciottolo, L.-E. Hsieh, Y. Li, M. J. LeCalire, J. B. Nice, R. Twaddle, C. L. Mora, M. Young, J. Angeles, C. Lau, C. Jin, K. Elliott, m. sun

This study develops a multivalent exosome-based vaccine platform that effectively induces strong immune responses against multiple viruses using minimal protein and no adjuvant.

bioRxiv · Jul 13, 2023Immunology

Identifying size-dependent toxin sorting in bacterial outer membrane vesicles

A. N. Singh, J. B. Nice, A. C. Brown, N. J. Wittenberg

This study uses fluorescence imaging to show that larger OMVs from A. actinomycetemcomitans are more likely to contain leukotoxin, revealing size-dependent toxin sorting.

bioRxiv · May 3, 2023 · PreprintBiophysics

Nanograms of SARS-CoV-2 Spike Protein Delivered by Exosomes Induce Potent Neutralization of Both Delta and Omicron Variants.

M. Cacciottolo, Y. Li, J. B. Nice, M. J. LeClaire, R. Twaddle, C. L. Mora, S. Y. Adachi, M. Young, J. Angeles, K. Elliott, M. Sun

This study demonstrates that exosomes delivering nanogram amounts of SARS-CoV-2 Spike protein induce potent neutralization against Delta and Omicron variants and enhance T cell responses.

bioRxiv · Mar 20, 2023Immunology

Exosome based multivalent vaccine: achieving potent immunization, broadened reactivity, and strong T cell responses with nanograms of proteins

M. Cacciottolo, J. B. Nice, Y. Li, M. J. LeClaire, R. Twaddle, C. L. Mora, S. Y. Adachi, E. R. Chin, M. Young, J. Angeles, K. Elliott, M. Sun

This paper develops a multivalent exosome-based vaccine using nanogram doses of SARS-CoV-2 proteins without adjuvant, showing strong immune responses and cross-reactivity against variants.

bioRxiv · Jan 10, 2023 · PreprintImmunology

Separation of heterogeneous Aggregatibacter actinomycetemcomitans outer membrane vesicles reveals that toxin sorting is driven by surface-associated DNA

J. B. Nice, S. M. Collins, S. M. Agro, A. Sinani, S. D. Moros, L. M. Pasch, A. C. Brown

The paper investigates how surface-associated DNA drives the selective sorting of the toxin LtxA to large outer membrane vesicles in Aggregatibacter actinomycetemcomitans.

bioRxiv · Jul 11, 2022 · PreprintMicrobiology