E. S. Giotis

This study investigates enzalutamide's antiviral effects against seasonal coronaviruses and identifies differences in viral-androgen signaling interactions between HCoV-229E and HCoV-OC43.

The study detects neutralizing antibodies against henipavirus, Nipah virus, and bat influenza in Eidolon helvum bats in Nigeria, suggesting a potential zoonotic spillover risk.

This study shows that primary human macrophages do not support SARS-CoV-2 replication and exhibit a limited cytokine response, unlike influenza viruses which induce strong IFN-β and proinflammatory cytokines.

This study compares the transcriptomic responses of inbred chicken lines to IBDV infection, finding that severe disease correlates with enhanced inflammation and faster pro-inflammatory gene induction in bursal cells.

This study identifies FPV184 as a Fowlpox virus protein that suppresses host IFN responses by inhibiting promoter activation and localizing to viral lateral bodies.

This study shows that chicken cGAS detects fowlpox virus DNA, triggering type-I interferon production and regulating macrophage effector functions like MHC-II expression.

This study compares the innate antiviral responses of two IBDV strains, showing that the very virulent UK661 strain suppresses IFN and proinflammatory gene expression more than the classical F52/70 strain, mediated in part by the VP4 protein.

This study identifies HLA-DR as a receptor for bat influenza A-like H17N10 virus entry into mammalian cells, revealing a novel mechanism distinct from classical influenza A viruses.

This study compares gene expression in chicken B cells infected with attenuated and very virulent IBDV strains to identify differences in immune response and virulence factors.