E. S. J. Smith

This study investigates the intestinal barrier function in naked mole-rats, finding reduced gut permeability and diminished secretory responses compared to mice.

This study identifies a tumor-suppressive strategy in naked mole-rats that couples regenerative cell turnover with a tumor-hostile stromal niche to prevent cancer.

This paper identifies GPR35 as a target for non-opioid analgesics by showing it inhibits TRPA1-mediated colonic hypersensitivity through suppression of Substance P release.

This study develops an endogenous lung cancer model in naked mole-rats, showing tumor initiation more closely resembles human tumors than in mice.

This study shows IL-13 sensitizes colonic nociceptors via JAK and p38 MAPK signaling, offering therapeutic targets for visceral pain in gastrointestinal diseases.

This study shows that ADAM10 shedding activity is impaired in naked mole-rat fibroblasts due to deficient phosphatidylserine externalization, which can be rescued by overexpressing ANO6.

This paper evaluates a short film's impact on public understanding and stigma around chronic gastrointestinal conditions through surveys and interviews.