PathologybioRxivPreprint
Ceramide synthase 6 (CerS6) promotes alcohol-induced fatty liver by promoting metabolic dysfunction and upregulating lipid droplet-associated proteins
S. Jeon, E. Scorletti, D. Buyco…·R. M. Carr
This study shows that deleting CerS6 reduces alcohol-induced fatty liver and improves glucose homeostasis in mice, and links CerS6 expression to ALD progression in humans.
DOI 10.1101/2022.11.03.514971