PhysiologybioRxivPreprint
Loss of SUMO-specific protease 2 causes isolated glucocorticoid deficiency by blocking adrenal cortex zonal transdifferentiation
D. Dufour, T. Dumontet, I. Sahut-Barnola…·A. Martinez
This study shows that loss of SENP2 causes adrenal cortex zonal defects and glucocorticoid deficiency by disrupting transdifferentiation and signaling pathways.
DOI 10.1101/2022.02.08.479354