D. Dufour

Sexually dimorphic activation of innate antitumour immunity prevents adrenocortical carcinoma development

This study shows that sexually dimorphic activation of innate antitumour immunity prevents adrenocortical carcinoma development, with male-specific macrophage responses driving tumour regression.

Loss of SUMO-specific protease 2 causes isolated glucocorticoid deficiency by blocking adrenal cortex zonal transdifferentiation

This study shows that loss of SENP2 causes adrenal cortex zonal defects and glucocorticoid deficiency by disrupting transdifferentiation and signaling pathways.

Steroidogenic factor-1 lineage origin of skin lesions in Carney complex syndrome

This study identifies dermal fibroblasts as the origin of skin lesions in Carney complex by showing their pro-melanogenic activity under PKA signaling disruption.

PKA drives paracrine crisis and WNT4-dependent testis tumor in Carney complex

The paper investigates the role of PKA in Carney complex testis tumors, showing that Prkar1a mutations in both stromal and Sertoli cells drive LCCSCTs via WNT4-dependent paracrine signaling.

Causes and biophysical consequences of cellulose production by Pseudomonas fluorescens SBW25 at the air-liquid interface

The paper investigates cellulose production by Pseudomonas fluorescens SBW25 at the air-liquid interface, revealing environmental signals that activate cellulose synthesis and resulting biophysical consequences.