Author

D. Breault

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioengineering· 1 Cell Biology· 1 Physiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:cell signaling & trafficking· 2 Research Focus:cell type annotation· 2 Research Focus:development & morphogenesis· 2 Organism:human· 2 Organism:mouse· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:clustering· 1

Frequent Co-Authors

A. Lampejo· 1 shared A. Levasseur· 1 shared A. M. Lefrancois-Martinez· 1 shared A. Martinez· 1 shared C. Lucas· 1 shared C. Y. Park· 1 shared D. Dufour· 1 shared E. Pussard· 1 shared

Activity by Year

2019-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 22 mutual co-author links

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1 shared paperBioengineering

A. Lampejo

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3 papers

Recent·Most cited

Loss of SUMO-specific protease 2 causes isolated glucocorticoid deficiency by blocking adrenal cortex zonal transdifferentiation

D. Dufour, T. Dumontet, I. Sahut-Barnola, M. Onzon, E. Pussard, J. Wilmouth, J. Olabe, C. Lucas, A. Levasseur, J.-C. Pointud, F. Roucher-Boulez, I. Tauveron, G. Bossis, D. Breault, E. T. Yeh, , A. Martinez

This study shows that loss of SENP2 causes adrenal cortex zonal defects and glucocorticoid deficiency by disrupting transdifferentiation and signaling pathways.

bioRxiv · Feb 8, 2022 · PreprintPhysiology

Stiffness Regulates Intestinal Stem Cell Fate

S. He, L. Peng, W. Kang, P. Cheung, T. Xu, M. Mana, C. Y. Park, H. Wang, S. Imada, J. O. Russell, J. Wang, R. Wang, Z. Zhou, K. Chetal, E. Stas, , N. Saeidi

This study shows that matrix stiffness affects intestinal stem cell fate by reducing Lgr5high ISCs and promoting differentiation into goblet cells, mediated by YAP nuclear translocation.

bioRxiv · Mar 15, 2021Cell Biology

Niche-inspired synthetic matrices for epithelial organoid culture

V. Hernandez-Gordillo, T. Kassis, A. Lampejo, G. Choi, M. E. Gamboa, J. S. Gnecco, D. Breault, R. Carrier, L. G. Griffith

This study develops synthetic matrices that support human organoid growth by mimicking the niche environment, showing that local biophysical cues, not bulk properties, drive organoid formation.

bioRxiv · Oct 16, 2019Bioengineering