Author

E. Ural

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Bioengineering· 4 Cancer Biology· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Research Focus:cell signaling & trafficking· 3 Approach:experimental assay· 3 Research Focus:host-pathogen & immune response· 3 Assay:proteomics· 3 Research Focus:cell type annotation· 2 Assay:metabolomics· 2 Approach:statistical model· 2 Approach:biophysical modeling· 1

Frequent Co-Authors

C. H. Contag· 5 shared C. V. Maduka· 5 shared M. Alhaj· 4 shared M. M. Kuhnert· 4 shared R. Narayan· 4 shared A. Tundo· 3 shared A. V. Makela· 3 shared K. D. Hankenson· 3 shared

Activity by Year

2022-2023 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

5 shared papersBioengineering

C. H. Contag

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

Regulating the proinflammatory response to implanted composite biomaterials comprising polylactide and hydroxyapatite by targeting immunometabolism

C. V. Maduka, A. V. Makela, E. Ural, K. B. Stivers, M. M. Kuhnert, A. Tundo, M. Alhaj, E. Hoque Apu, N. Ashammakhi, K. D. Hankenson, R. Narayan, J. H. Elisseeff, C. H. Contag

This study modulates the inflammatory response to PLA-HA biomaterials by targeting immunometabolism, reducing proinflammatory cells and increasing pro-regenerative ones.

bioRxiv · Oct 21, 2023Bioengineering

Immunometabolic cues recompose and reprogram the microenvironment around biomaterials

C. V. Maduka, A. D. Schmitter-Sanchez, A. V. Makela, E. Ural, K. B. Stivers, H. Pope, M. M. Kuhnert, O. M. Habeeb, A. Tundo, M. Alhaj, A. Kiselev, S. Chen, A. J. Olive, K. D. D. Hankenson, R. Narayan, , C. H. Contag

The paper shows that immunometabolic cues around biomaterials influence immune cell trafficking and microenvironment composition, promoting a pro-regenerative state through metabolic reprogramming.

bioRxiv · Jul 30, 2023Bioengineering

Flavinated SDHA Underlies the Change in Intrinsic Optical Properties of Oral Cancers

T. Marumo, C. V. Maduka, E. Ural, E. H. Apu, S.-J. Chung, N. S. van den Berg, Q. Zhou, B. A. Martin, E. L. Rosenthal, T. Shibahara, C. H. Contag

The paper identifies flavinated SDHA as responsible for altered autofluorescence in oral cancer cells, linking it to metabolic changes and potential diagnostic and therapeutic targets.

bioRxiv · Jul 30, 2023Cancer Biology

Stereochemistry Determines Immune Cellular Responses to Polylactide Implants

C. V. Maduka, M. Alhaj, E. Ural, M. M. Kuhnert, O. M. Habeeb, A. L. Schilmiller, K. D. Hankenson, S. B. Goodman, R. Narayan, C. H. Contag

This study shows that PLA stereochemistry affects immune responses through differential metabolic changes in macrophages and fibroblasts, with stereocomplex PLA increasing proinflammatory cytokines via glycolysis.

bioRxiv · Oct 27, 2022Bioengineering

Polylactide Degradation Activates Immune Cells by Metabolic Reprogramming

C. V. Maduka, M. Alhaj, E. Ural, M. O. Habeeb, M. M. Kuhnert, K. Smith, A. V. Makela, H. Pope, S. Chen, J. M. Hix, C. L. Mallet, S.-J. Chung, M. Hakun, A. Tundo, K. R. Zinn, , C. H. Contag

This study shows that PLA degradation products reprogram cell metabolism, leading to immune activation and inflammation, and demonstrates that targeting metabolism can reduce inflammation and improve biocompatibility.

bioRxiv · Sep 22, 2022Bioengineering